update range to 10000 bp
locus tag: FAM13496-i1-1.1_001098 genome: FAM13496-i1-1.1
species: Streptococcus thermophilus taxid: 1308

Annotations

Type Name Description Pathways
KEGG reaction
 R08244 6-thioxanthine 5'-monophosphate:L-glutamine amido-ligase (AMP-forming); 6-Thioxanthine 5'-monophosphate + ATP + L-Glutamine + H2O <=> 6-Thioguanosine monophosphate + AMP + Diphosphate + L-Glutamate kornec00983
KEGG reaction
 R01231 Xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming); ATP + Xanthosine 5'-phosphate + L-Glutamine + H2O <=> AMP + Diphosphate + GMP + L-Glutamate kornec00230kornec01100
KEGG reaction
 R01230 Xanthosine-5'-phosphate:ammonia ligase (AMP-forming); ATP + Xanthosine 5'-phosphate + Ammonia <=> AMP + Diphosphate + GMP kornec00230kornec01100
Ortholog
 N0.HOG0001368 glutamine-hydrolyzing GMP synthase
KEGG gene
 K01951 guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] kornec00230kornec00983kornec01100
Gene Code
 guaA
Gene Ontology
 GO:1901659 glycosyl compound biosynthetic process
Gene Ontology
 GO:1901657 glycosyl compound metabolic process
Gene Ontology
 GO:1901576 organic substance biosynthetic process
Gene Ontology
 GO:1901566 organonitrogen compound biosynthetic process
Gene Ontology
 GO:1901564 organonitrogen compound metabolic process
Gene Ontology
 GO:1901362 organic cyclic compound biosynthetic process
Gene Ontology
 GO:1901360 organic cyclic compound metabolic process
Gene Ontology
 GO:1901293 nucleoside phosphate biosynthetic process
Gene Ontology
 GO:1901137 carbohydrate derivative biosynthetic process
Gene Ontology
 GO:1901135 carbohydrate derivative metabolic process
Gene Ontology
 GO:1901070 guanosine-containing compound biosynthetic process
Gene Ontology
 GO:1901068 guanosine-containing compound metabolic process
Gene Ontology
 GO:0090407 organophosphate biosynthetic process
Gene Ontology
 GO:0072522 purine-containing compound biosynthetic process
Gene Ontology
 GO:0072521 purine-containing compound metabolic process
Gene Ontology
 GO:0071704 organic substance metabolic process
Gene Ontology
 GO:0055086 nucleobase-containing small molecule metabolic process
Gene Ontology
 GO:0046483 heterocycle metabolic process
Gene Ontology
 GO:0046390 ribose phosphate biosynthetic process
Gene Ontology
 GO:0046129 purine ribonucleoside biosynthetic process
Gene Ontology
 GO:0046128 purine ribonucleoside metabolic process
Gene Ontology
 GO:0046037 GMP metabolic process
Gene Ontology
 GO:0044283 small molecule biosynthetic process
Gene Ontology
 GO:0044281 small molecule metabolic process
Gene Ontology
 GO:0044271 cellular nitrogen compound biosynthetic process
Gene Ontology
 GO:0044249 cellular biosynthetic process
Gene Ontology
 GO:0044238 primary metabolic process
Gene Ontology
 GO:0044237 cellular metabolic process
Gene Ontology
 GO:0042455 ribonucleoside biosynthetic process
Gene Ontology
 GO:0042451 purine nucleoside biosynthetic process
Gene Ontology
 GO:0042278 purine nucleoside metabolic process
Gene Ontology
 GO:0034654 nucleobase-containing compound biosynthetic process
Gene Ontology
 GO:0034641 cellular nitrogen compound metabolic process
Gene Ontology
 GO:0034404 nucleobase-containing small molecule biosynthetic process
Gene Ontology
 GO:0019693 ribose phosphate metabolic process
Gene Ontology
 GO:0019637 organophosphate metabolic process
Gene Ontology
 GO:0019438 aromatic compound biosynthetic process
Gene Ontology
 GO:0018130 heterocycle biosynthetic process
Gene Ontology
 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor
Gene Ontology
 GO:0016879 ligase activity, forming carbon-nitrogen bonds
Gene Ontology
 GO:0016874 ligase activity
Gene Ontology
 GO:0009987 cellular process
Gene Ontology
 GO:0009260 ribonucleotide biosynthetic process
Gene Ontology
 GO:0009259 ribonucleotide metabolic process
Gene Ontology
 GO:0009168 purine ribonucleoside monophosphate biosynthetic process
Gene Ontology
 GO:0009167 purine ribonucleoside monophosphate metabolic process
Gene Ontology
 GO:0009165 nucleotide biosynthetic process
Gene Ontology
 GO:0009163 nucleoside biosynthetic process
Gene Ontology
 GO:0009161 ribonucleoside monophosphate metabolic process
Gene Ontology
 GO:0009156 ribonucleoside monophosphate biosynthetic process
Gene Ontology
 GO:0009152 purine ribonucleotide biosynthetic process
Gene Ontology
 GO:0009150 purine ribonucleotide metabolic process
Gene Ontology
 GO:0009127 purine nucleoside monophosphate biosynthetic process
Gene Ontology
 GO:0009126 purine nucleoside monophosphate metabolic process
Gene Ontology
 GO:0009124 nucleoside monophosphate biosynthetic process
Gene Ontology
 GO:0009123 nucleoside monophosphate metabolic process
Gene Ontology
 GO:0009119 ribonucleoside metabolic process
Gene Ontology
 GO:0009117 nucleotide metabolic process
Gene Ontology
 GO:0009116 nucleoside metabolic process
Gene Ontology
 GO:0009058 biosynthetic process
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0006807 nitrogen compound metabolic process
Gene Ontology
 GO:0006796 phosphate-containing compound metabolic process
Gene Ontology
 GO:0006793 phosphorus metabolic process
Gene Ontology
 GO:0006753 nucleoside phosphate metabolic process
Gene Ontology
 GO:0006725 cellular aromatic compound metabolic process
Gene Ontology
 GO:0006177 GMP biosynthetic process
Gene Ontology
 GO:0006164 purine nucleotide biosynthetic process
Gene Ontology
 GO:0006163 purine nucleotide metabolic process
Gene Ontology
 GO:0006139 nucleobase-containing compound metabolic process
Gene Ontology
 GO:0003922 GMP synthase (glutamine-hydrolyzing) activity
Gene Ontology
 GO:0003921 GMP synthase activity
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Gene Product
 glutamine-hydrolyzing GMP synthase
Eggnog Protein
 EP:guaA
Eggnog Ortholog
 EO:COG0518
Eggnog Description
 ED:Catalyzes the synthesis of GMP from XMP
EC Number
 EC:6.3.5.2 GMP synthase (glutamine-hydrolysing); GMP synthetase (glutamine-hydrolysing); guanylate synthetase (glutamine-hydrolyzing); guanosine monophosphate synthetase (glutamine-hydrolyzing); xanthosine 5'-phosphate amidotransferase; guanosine 5'-monophosphate synthetase kornec00230kornec00983kornec01100

Occurs in the following pathway maps:

Pathway Description
kornec00230 Purine metabolism
kornec00983 Drug metabolism - other enzymes
kornec01100 Metabolic pathways

Sequences

Nucleotide sequence (GC-content: 43.6 %):

ATGACTAACATTTCTACTTTGAATGATGTGCAGAAAATCATTGTTCTAGACTATGGTAGCCAATACAATCAGCTGATTGCACGTCGTATTCGTGAATTTGGCGTTTTCTCTGAATTGAAGAGCCATAAAATTACTGCTGATGAAGTACGTGCCATCAATCCCATCGGGATCATACTTTCTGGTGGTCCCAACTCTGTTTATGCCGAAGATGCATTTGGTATTGACGAAGAAATTTTCGAGCTTGGTATCCCAATTCTTGGTATCTGTTACGGAATGCAACTTTTGACCCACAAACTCGGTGGTAAAGTTGTTCCGGCTGGTGAAGCAGGTAACCGTGAGTATGGCCAATCAACACTTCGCCTTCGTGCCCAATCAGAGCTCTTTGCTGGAACTCCTGAAGAACAAGTCGTTCTGATGAGCCACGGTGATGCTGTTACAGAAATTCCAGAAGGTTTCCATCTTGTTGGTGACTCAGTGGATTGCCCATTCGCTGCGATGGAAGATACTAAGAAAAACTTTTATGGTATCCAATTCCACCCAGAAGTTCGTCACACTGTATATGGTAACGACATTTTGAAAAACTTCGCTTTTAGTATATGTGGTGCCAAAGGTGACTGGTCAATGGCTAACTTCGTAGATATGCAAATTGCACAGATTCGTGAAACAGTTGGCGACCGCAAAGTCCTTCTTGGACTATCAGGTGGAGTTGATTCATCTGTTGTCGGTGTGCTCTTGCAAAAAGCTATTGGTGATCAATTGACATGTATCTTTGTTGACCACGGTCTTCTCCGTAAAGGTGAAGGCGACCAGGTTATGGAGATGCTGGGAGGTAAATTTGGCCTTAACATTATCCGTGTTGATGCTTCTAAACGCTTCCTTGATCTCTTGGCTGGTGTTGATGACCCTGAGAAAAAACGTAAAATCATCGGTAACGAATTTGTTCACGTTTTTGATGACGAAGCAAGCAAACTTAAAGGTGTTGACTTCCTAGCTCAAGGAACACTCTACACTGATATCATTGAATCAGGTACTGAAACAGCGCAAACAATCAAATCTCACCACAACGTTGGTGGTCTTCCAGAAGACATGCAGTTTGAATTGATTGAACCACTTAACACTCTCTTTAAAGATGAAGTGCGCGCTCTTGGTACTGAACTGGGAATGCCTGACGAGGTCGTTTGGCGCCAACCATTCCCAGGACCAGGACTTGCCATCCGTGTTATAGGTGAAATCACTGAAGAGAAACTTGAAACCGTTCGTGAGTCTGATGCTATTCTTCGCGAGGAAATCGCTAAGGCTGGTCTTGACCGTGATGTATGGCAATACTTCACTGTTAACACAGGCGTACGTTCTGTCGGTGTTATGGGTGACGGACGAACTTACGACTATACTATTGCTATCCGTGCTATCACTTCAATTGACGGTATGACAGCTGACTTTGCGAAACTTCCATGGGAGGTTCTCCAAAAGATTTCTGTTCGAATCGTTAACGAAGTTGATCACGTTAACCGTATCGTCTACGATATTACAAGTAAACCACCTGCAACTGTAGAGTGGGAATAA

Protein sequence:

MTNISTLNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITADEVRAINPIGIILSGGPNSVYAEDAFGIDEEIFELGIPILGICYGMQLLTHKLGGKVVPAGEAGNREYGQSTLRLRAQSELFAGTPEEQVVLMSHGDAVTEIPEGFHLVGDSVDCPFAAMEDTKKNFYGIQFHPEVRHTVYGNDILKNFAFSICGAKGDWSMANFVDMQIAQIRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKGEGDQVMEMLGGKFGLNIIRVDASKRFLDLLAGVDDPEKKRKIIGNEFVHVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGMPDEVVWRQPFPGPGLAIRVIGEITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAKLPWEVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE

GenBank Info

gene - guaA
locus_tag - FAM13496-i1-1.1_001098
EC_number - 6.3.5.2
inference - COORDINATES: similar to AA sequence:RefSeq:WP_009880616.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - glutamine-hydrolyzing GMP synthase
protein_id - extdb:FAM13496-i1-1.1_001098

Gene Locus

Located on scaffold FAM13496-i1-1_scf13

FAM13496-i1-1.1_001097
FAM13496-i1-1.1_001099