update range to 10000 bp
locus tag: FAM13496-i1-1.1_001143 genome: FAM13496-i1-1.1
species: Streptococcus thermophilus taxid: 1308

Annotations

Type Name Description Pathways
Gene Product
 threonine ammonia-lyase IlvA
KEGG reaction
 R00996 L-threonine ammonia-lyase (2-oxobutanoate-forming); L-Threonine <=> 2-Oxobutanoate + Ammonia kornec00260kornec00290kornec01100kornec01110kornec01230
KEGG reaction
 R00220 L-serine ammonia-lyase; L-Serine <=> Pyruvate + Ammonia kornec00260kornec01100kornec01110kornec01200kornec01230
Ortholog
 N0.HOG0001776 threonine ammonia-lyase IlvA
KEGG gene
 K01754 E4.3.1.19, ilvA, tdcB; threonine dehydratase [EC:4.3.1.19] kornec00260kornec00290kornec01100kornec01110kornec01200kornec01230
Gene Code
 ilvA
Gene Ontology
 GO:1901605 alpha-amino acid metabolic process
Gene Ontology
 GO:1901564 organonitrogen compound metabolic process
Gene Ontology
 GO:0071704 organic substance metabolic process
Gene Ontology
 GO:0044281 small molecule metabolic process
Gene Ontology
 GO:0044238 primary metabolic process
Gene Ontology
 GO:0044237 cellular metabolic process
Gene Ontology
 GO:0043436 oxoacid metabolic process
Gene Ontology
 GO:0019752 carboxylic acid metabolic process
Gene Ontology
 GO:0009987 cellular process
Gene Ontology
 GO:0009066 aspartate family amino acid metabolic process
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0006807 nitrogen compound metabolic process
Gene Ontology
 GO:0006566 threonine metabolic process
Gene Ontology
 GO:0006520 cellular amino acid metabolic process
Gene Ontology
 GO:0006082 organic acid metabolic process
Eggnog Protein
 EP:ilvA
Eggnog Ortholog
 EO:COG1171
Eggnog Description
 ED:Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)
EC Number
 EC:4.3.1.19 threonine ammonia-lyase; threonine deaminase; L-serine dehydratase; serine deaminase; L-threonine dehydratase; threonine dehydrase; L-threonine deaminase; threonine dehydratase; L-threonine hydro-lyase (deaminating); L-threonine ammonia-lyase kornec00260kornec00290kornec01100kornec01110

Occurs in the following pathway maps:

Pathway Description
kornec00260 Glycine, serine and threonine metabolism
kornec00290 Valine, leucine and isoleucine biosynthesis
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01200 Carbon metabolism
kornec01230 Biosynthesis of amino acids

Sequences

Nucleotide sequence (GC-content: 40.2 %):

ATGATTACTGCAAATGATATCGTAAAGGCTAATGAAGTCTTAAAAAACGTGGTGGAGCGTACCCCACTAGATTTTGATCGCTACTTATCTGAAAAATATGGAGCGACTATTTATATTAAAAAAGAAAATATGCAAAAGGTACGTTCCTTTAAATTACGTGGTGCCTACTATGCGATCCATCAGTTAAGTGATGAAGACAAGGAACATGGTGTGGTCTGTGCATCAGCCGGAAACCATGCCCAAGGTGTTGCTTATACTTGTAATGAAATGAAGATTCCTGCAACTATCTTTATGCCAGTAACAACCCCTCTCCAAAAAATTGGTCAAGTACGTTTCTTTGGTGGCAAGTTTGTAACAATTAAATTGGTTGGAGATACCTTTGATGAATCTGCTAAAGCGGCACAAGAGTATACGAAGTCGGAAGGGATGACTTTTATTGATCCATTCGATGATTATAATGTCCAAGCGGGTCAAGGAACTGTTGCTTATGAAATTTATGAGCAAGCTCAAGAGGAAGGTGTTTCCTTTGATAGTATCTTAGTGCCGGTAGGTGGGGGTGGACTCATCTCTGGTGTGGCTACCTATATCAAGGATGTGGCACCCTCTATAGAGGTTGTAGGTGTTGAGGCTAGTGGTGCTCGTAGTATGCGTGCAGCCTTTGACCATGGTTATCCTGTAAAACTTGAAAAGATTGATAAGTTTGCAGATGGGATTGCTGTCCAAAAGGTAGGTGCAAAAACTTACGAAGTTGCTCGTAAATATGTAGATCGTCTCTTGGGAGTTGATGAAGGATTAATCTCAGAAACCTTAATTGATATGTACTCGAAGGTTGGTACTATCGCAGAACCTGCAGGGGCAGCATCAGTTGCGGCACTTGAAGTGATTAAAGATGAAATTAAAGGAAAAACTATCGTTTGCATCATTTCAGGCGGTAATAATGATATCAACCGTATGCCAGAGATGGAAGAACGTGCCCTTATCTATGATGGGATCAAGCACTATTTTGTGGTTAATTTCCCACAACGTCCAGGAGCCCTTCGTGAGTTTGTAAATGATATCTTAGGGCCAAATGATGACATTACTCGTTTTGAGTACATCAAACGTGCCAATAAAGGGAAAGGTCCAGTTCTCATTGGTATAGCTCTTAGTGATAAGAATGATTATGATGGTCTTCTTGAGCGTCTTTCTGAATTTGATCCAAGTTACATTAATCTTAACGGAAATGAAACACTTTACAACATGCTTGTCTGA

Protein sequence:

MITANDIVKANEVLKNVVERTPLDFDRYLSEKYGATIYIKKENMQKVRSFKLRGAYYAIHQLSDEDKEHGVVCASAGNHAQGVAYTCNEMKIPATIFMPVTTPLQKIGQVRFFGGKFVTIKLVGDTFDESAKAAQEYTKSEGMTFIDPFDDYNVQAGQGTVAYEIYEQAQEEGVSFDSILVPVGGGGLISGVATYIKDVAPSIEVVGVEASGARSMRAAFDHGYPVKLEKIDKFADGIAVQKVGAKTYEVARKYVDRLLGVDEGLISETLIDMYSKVGTIAEPAGAASVAALEVIKDEIKGKTIVCIISGGNNDINRMPEMEERALIYDGIKHYFVVNFPQRPGALREFVNDILGPNDDITRFEYIKRANKGKGPVLIGIALSDKNDYDGLLERLSEFDPSYINLNGNETLYNMLV

GenBank Info

gene - ilvA
locus_tag - FAM13496-i1-1.1_001143
EC_number - 4.3.1.19
inference - COORDINATES: similar to AA sequence:RefSeq:NP_720699.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - threonine ammonia-lyase IlvA
protein_id - extdb:FAM13496-i1-1.1_001143

Gene Locus

Located on scaffold FAM13496-i1-1_scf14

FAM13496-i1-1.1_001142
FAM13496-i1-1.1_001144