update range to 10000 bp
locus tag: FAM13496-i1-1.1_001209 genome: FAM13496-i1-1.1
species: Streptococcus thermophilus taxid: 1308

Annotations

Type Name Description Pathways
KEGG reaction
 R05070 (R)-2,3-Dihydroxy-3-methylpentanoate hydro-lyase; (R)-2,3-Dihydroxy-3-methylpentanoate <=> (S)-3-Methyl-2-oxopentanoic acid + H2O kornec00290kornec01100kornec01110kornec01210kornec01230
KEGG reaction
 R04441 (R)-2,3-Dihydroxy-3-methylbutanoate hydro-lyase; (R)-2,3-Dihydroxy-3-methylbutanoate <=> 3-Methyl-2-oxobutanoic acid + H2O kornec00290kornec00770kornec01100kornec01110kornec01210kornec01230
KEGG reaction
 R01209 2,3-Dihydroxy-3-methylbutanoate hydro-lyase; 2,3-Dihydroxy-3-methylbutanoate <=> 3-Methyl-2-oxobutanoic acid + H2O
Ortholog
 N0.HOG0001827 dihydroxy-acid dehydratase
KEGG gene
 K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] kornec00290kornec00770kornec01100kornec01110kornec01210kornec01230
Gene Code
 ilvD
Gene Ontology
 GO:0016836 hydro-lyase activity
Gene Ontology
 GO:0016835 carbon-oxygen lyase activity
Gene Ontology
 GO:0016829 lyase activity
Gene Ontology
 GO:0004160 dihydroxy-acid dehydratase activity
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Eggnog Protein
 EP:ilvD
Eggnog Ortholog
 EO:COG0129
Eggnog Description
 ED:Belongs to the IlvD Edd family
EC Number
 EC:4.2.1.9 dihydroxy-acid dehydratase; acetohydroxyacid dehydratase; alpha,beta-dihydroxyacid dehydratase; 2,3-dihydroxyisovalerate dehydratase; alpha,beta-dihydroxyisovalerate dehydratase; dihydroxy acid dehydrase; DHAD; 2,3-dihydroxy-acid hydro-lyase kornec00290kornec00770kornec01100kornec01110
Gene Product
 dihydroxy-acid dehydratase

Occurs in the following pathway maps:

Pathway Description
kornec00290 Valine, leucine and isoleucine biosynthesis
kornec00770 Pantothenate and CoA biosynthesis
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01210 2-Oxocarboxylic acid metabolism
kornec01230 Biosynthesis of amino acids

Sequences

Nucleotide sequence (GC-content: 44.7 %):

ATGGAGGAAAATATCGTGTCTGAAAATAACATGAAACACCGTTCTTCTGTCTACGATAGCATGGTTAAATCACCTAACCGTGCTATGCTTCGTGCGACTGGGATGACGGATGATAGTTTTGAAAAGCCTATTGTTGGGGTTATCTCAACTTGGGCTGAGAACACGCCATGTAATATCCACTTGCACGGTTTTGGTCAAATTGCCAAAGAGGGTGTCAAAGATGCGGGTGCTTGGCCAGTTCAATTTGGTACAATTACCGTTGCAGATGGTATTGCCATGGGGACACCAGGGATGCGTTTCTCATTGACATCTCGTGATATTATTGCTGACTCAATTGAAGCTGCTATGGGTGGTCACAATGTCGATGCCTTTGTTGCTATTGGTGGCTGTGATAAGAACATGCCAGGTTCAATGATTGCTATTGCCAACATGGATATTCCAGCTATTTTTGCTTACGGTGGTACGATTGCACCGGGTAATCTTAACGGTAAGGATATCGACTTGGTTTCTGTTTTCGAAGGTATCGGTAAATGGAACCACGGAGATATGACTGCCGAAGAGGTTAAAAATCTTGAATGTAATGCCTGCCCTGGCCCTGGTGGTTGTGGTGGTATGTATACTGCTAACACAATGGCAACAGCAATTGAGGTTATGGGGATGAGCCTTCCAGGATCATCATCTCACCCTGCAGAATCAGCTGAGAAGAAGGCTGATATCGAAGAAGCAGGTCGTGCAGTTGTAAAAATGCTAGAAATGGGACTTAAGCCATCAGATATCTTGACACGTGAAGCCTTTGAAGATGCCATCACAGTTACAATGGCGCTTGGCGGTTCAACAAATGCCACCCTTCACTTGCTTGCTATCGCTCATGCGGCTAACGTTGATTTAACGCTTGAAGACTTCAACGATTTCCAAGAGCGCGTGCCTCACTTGGCTGACTTGAAGCCTTCAGGTCAGTATGTCTTCCAAGACCTTTACAATGTTGGTGGTGTGCCAGCCGTTATGAAATATCTTCTTAAGAATGGTTTTCTTCACGGTGATCGTATCACGTGTACTGGTAAGACTGTTGCAGAAAATTTGGAAGCTTTCGATGATTTGACACCAGGTCAAAAAGTTATCATGCCACTTGAAAATCCTAAACGTGCCGATGGTCCATTGATTATCTTGAAAGGTAACTTGGCCCCAGAAGGTGCTGTTGCCAAAGTATCAGGTGTTAAAGTGCGTAACATTACTGGTCCTGCTAAAGTATTTGACTCAGAAGAAGATGCCATCGAGGCAGTTCTTTCTGACGAAATCGTTGACGGCGATGTAGTTGTTGTACGTTTTGTAGGTCCTAAGGGTGGTCCTGGTATGCCAGAAATGTTGTCATTGTCATCAATGATTGTTGGTAAAGGACAAGGAGACAAGGTTGCCCTCTTGACTGATGGACGTTTCTCAGGTGGTACTTACGGACTTGTTGTAGGTCATATTGCTCCTGAAGCTCAAGTTGGTGGACCGATTGCCTACCTCCGTACAGGTGATATGGTTACAGTTGACCAGGATACCAAAGAAATCACTATGCATGTACCAGACGAAGAGTTGGCGAAACGTAAAGCAGAAACTGAGTTACCACCACTTTATAGCCGTGGTGTCCTCGGTAAGTATGCTCACATCGTTTCATCAGCATCACGTGGTGCGGTTACTGACTTCTGGAATATGGATAAATCAGGTAAAGCTTAA

Protein sequence:

MEENIVSENNMKHRSSVYDSMVKSPNRAMLRATGMTDDSFEKPIVGVISTWAENTPCNIHLHGFGQIAKEGVKDAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDIIADSIEAAMGGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLNGKDIDLVSVFEGIGKWNHGDMTAEEVKNLECNACPGPGGCGGMYTANTMATAIEVMGMSLPGSSSHPAESAEKKADIEEAGRAVVKMLEMGLKPSDILTREAFEDAITVTMALGGSTNATLHLLAIAHAANVDLTLEDFNDFQERVPHLADLKPSGQYVFQDLYNVGGVPAVMKYLLKNGFLHGDRITCTGKTVAENLEAFDDLTPGQKVIMPLENPKRADGPLIILKGNLAPEGAVAKVSGVKVRNITGPAKVFDSEEDAIEAVLSDEIVDGDVVVVRFVGPKGGPGMPEMLSLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQVGGPIAYLRTGDMVTVDQDTKEITMHVPDEELAKRKAETELPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGKA

GenBank Info

gene - ilvD
locus_tag - FAM13496-i1-1.1_001209
EC_number - 4.2.1.9
inference - COORDINATES: similar to AA sequence:RefSeq:WP_002891655.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - dihydroxy-acid dehydratase
protein_id - extdb:FAM13496-i1-1.1_001209

Gene Locus

Located on scaffold FAM13496-i1-1_scf15

FAM13496-i1-1.1_001208
FAM13496-i1-1.1_001210