update range to 10000 bp
locus tag: FAM13496-i1-1.1_001331 genome: FAM13496-i1-1.1
species: Streptococcus thermophilus taxid: 1308

Annotations

Type Name Description Pathways
KEGG reaction
 R04946 O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine); O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate kornec00450kornec01100
KEGG reaction
 R04945 O-Acetylhomoserine succinate-lyase (adding cysteine); O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
KEGG reaction
 R04944 O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine); O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate kornec00450kornec01100
KEGG reaction
 R03260 O-Succinyl-L-homoserine succinate-lyase (adding cysteine); O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate kornec00270kornec01100kornec01110kornec01230
KEGG reaction
 R03217 O-Acetyl-L-homoserine succinate-lyase (adding cysteine); O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate kornec00270kornec01100
KEGG reaction
 R02508 Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
KEGG reaction
 R01288 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide); O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate kornec00270kornec00920kornec01100
KEGG reaction
 R00999 O-Succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming); O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia kornec00270kornec01100
Ortholog
 N0.HOG0000806 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
KEGG gene
 K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] kornec00270kornec00450kornec00920kornec01100kornec01110kornec01230
Gene Ontology
 GO:0016846 carbon-sulfur lyase activity
Gene Ontology
 GO:0016829 lyase activity
Gene Ontology
 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Gene Ontology
 GO:0016740 transferase activity
Gene Ontology
 GO:0004123 cystathionine gamma-lyase activity
Gene Ontology
 GO:0003962 cystathionine gamma-synthase activity
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Eggnog Protein
 EP:metB
Eggnog Ortholog
 EO:COG0626
Eggnog Description
 ED:cystathionine
EC Number
 EC:2.5.1.48 cystathionine gamma-synthase; O-succinyl-L-homoserine succinate-lyase (adding cysteine); O-succinylhomoserine (thiol)-lyase; homoserine O-transsuccinylase (ambiguous); O-succinylhomoserine synthase; O-succinylhomoserine synthetase; cystathionine synthase; cystathionine synthetase; homoserine transsuccinylase (ambiguous); 4-O-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase kornec00270kornec00450kornec00920kornec01100kornec01110
Gene Product
 cystathionine gamma-synthase

Occurs in the following pathway maps:

Pathway Description
kornec00270 Cysteine and methionine metabolism
kornec00450 Selenocompound metabolism
kornec00920 Sulfur metabolism
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01230 Biosynthesis of amino acids

Sequences

Nucleotide sequence (GC-content: 40.6 %):

ATGACACAAGATTATCAATTAGAAACTATTTTGGCACATGCAGGAATCAATTCTGATGAAGCAACAGGAGCTTTAGCTTCACCGATTCATTTTTCAACAACTTACCAACATCCAGAATTCGGACAGTCTACTGGTTTTGACTATACACGAACTAAAAATCCAACGCGTGCAACAGTGGAAAAAACGCTAGCAGCTATTGAAAAAGCGGATTATGCTATTGCGACAAGTTCAGGGATGAGCGCTATTGTTTTGGCCTTTGAAATTTTCCCTGTAGGTAGCAAGGTTGTCGCTGCCCGTGACCTTTATGGAGGTTCTTTCCGTTGGTTCAACGATAAAGAAAAAGAAGGACGTTTTTTCTTTGAATACACCAATACAGAAGATGAGATGATTGCGGCTATTGCAGAAGATACCGATATTGTCTACATTGAAACACCGACAAACCCACTTATGATTGAGTTTGATATTGAGAAAGTAGCTCAGACTGCCCATGAAAAGGGTGCGGTGGTTATTGTTGATAATACTTTCTATAGCCCAATCTACCAAACCCCGATTACTCAAGGTGCTGATATCGTTGTACATTCAGCTACTAAATACCTATCAGGGCATAATGATGTTTTAGCTGGTGTTGTTGTGACTAGCAATCCAGAATTCTACGATAAACTTTATTATAACCTCAATACGACTGGTCCGAACTTGTCCCCATTTGATAGCTATATGCTCATGCGTGGACTTAAGACCCTAAAACTTCGTATGGAGGCATCAACGGCTAATGCTAAAGAAGTTGTGGCGTTCTTAGAAAAGTCCCCAGCTGTTAAAGAGGTTCTCTACCCAGGTAAGGGTGGGATGATTTCCTTCAAAGTGGCTAACCAAGATAAGATTCCAACTATTATCAATACTCTTAAGGTCTTTACCTTTGCGGAGAGTCTGGGTGGTGTTGAAAGTTTGATTACTTACCCAGCAACACAAACTCACGCAGATATTCCAAGTGAAGTACGTGCTTCGTATGGATTAACGGATGACTTGCTTCGTCTTTCAATTGGTATTGAAGCAGCAGAGGATTTGATTGCTGACTTGGAAAATGCCCTTAGTCTTTAA

Protein sequence:

MTQDYQLETILAHAGINSDEATGALASPIHFSTTYQHPEFGQSTGFDYTRTKNPTRATVEKTLAAIEKADYAIATSSGMSAIVLAFEIFPVGSKVVAARDLYGGSFRWFNDKEKEGRFFFEYTNTEDEMIAAIAEDTDIVYIETPTNPLMIEFDIEKVAQTAHEKGAVVIVDNTFYSPIYQTPITQGADIVVHSATKYLSGHNDVLAGVVVTSNPEFYDKLYYNLNTTGPNLSPFDSYMLMRGLKTLKLRMEASTANAKEVVAFLEKSPAVKEVLYPGKGGMISFKVANQDKIPTIINTLKVFTFAESLGGVESLITYPATQTHADIPSEVRASYGLTDDLLRLSIGIEAAEDLIADLENALSL

GenBank Info

locus_tag - FAM13496-i1-1.1_001331
EC_number - 2.5.1.48
inference - COORDINATES: similar to AA sequence:RefSeq:WP_002946733.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - cystathionine gamma-synthase
protein_id - extdb:FAM13496-i1-1.1_001331

Gene Locus

Located on scaffold FAM13496-i1-1_scf18

FAM13496-i1-1.1_001330
FAM13496-i1-1.1_001332