| Type | Name | Description | Pathways |
|---|---|---|---|
|
KEGG reaction
|
R00382 | (deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming, NMN-forming); NAD+ + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Nicotinamide D-ribonucleotide + DNA(n+m) | |
|
Gene Product
|
NAD-dependent DNA ligase LigA | ||
|
Ortholog
|
N0.HOG0001434 | NAD-dependent DNA ligase LigA | |
|
Gene Code
|
ligA | ||
|
KEGG gene
|
K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | kornec03030kornec03410kornec03420kornec03430 |
|
Gene Ontology
|
GO:1901360 | organic cyclic compound metabolic process | |
|
Gene Ontology
|
GO:0140097 | catalytic activity, acting on DNA | |
|
Gene Ontology
|
GO:0090304 | nucleic acid metabolic process | |
|
Gene Ontology
|
GO:0071944 | cell periphery | |
|
Gene Ontology
|
GO:0071704 | organic substance metabolic process | |
|
Gene Ontology
|
GO:0051716 | cellular response to stimulus | |
|
Gene Ontology
|
GO:0051103 | DNA ligation involved in DNA repair | |
|
Gene Ontology
|
GO:0050896 | response to stimulus | |
|
Gene Ontology
|
GO:0046872 | metal ion binding | |
|
Gene Ontology
|
GO:0046483 | heterocycle metabolic process | |
|
Gene Ontology
|
GO:0044464 | obsolete cell part | |
|
Gene Ontology
|
GO:0044444 | obsolete cytoplasmic part | |
|
Gene Ontology
|
GO:0044424 | obsolete intracellular part | |
|
Gene Ontology
|
GO:0044260 | cellular macromolecule metabolic process | |
|
Gene Ontology
|
GO:0044238 | primary metabolic process | |
|
Gene Ontology
|
GO:0044237 | cellular metabolic process | |
|
Gene Ontology
|
GO:0043170 | macromolecule metabolic process | |
|
Gene Ontology
|
GO:0043169 | cation binding | |
|
Gene Ontology
|
GO:0043167 | ion binding | |
|
Gene Ontology
|
GO:0040007 | growth | |
|
Gene Ontology
|
GO:0034641 | cellular nitrogen compound metabolic process | |
|
Gene Ontology
|
GO:0033554 | cellular response to stress | |
|
Gene Ontology
|
GO:0030312 | external encapsulating structure | |
|
Gene Ontology
|
GO:0016886 | ligase activity, forming phosphoric ester bonds | |
|
Gene Ontology
|
GO:0016874 | ligase activity | |
|
Gene Ontology
|
GO:0016020 | membrane | |
|
Gene Ontology
|
GO:0009987 | cellular process | |
|
Gene Ontology
|
GO:0008152 | metabolic process | |
|
Gene Ontology
|
GO:0008150 | biological_process | |
|
Gene Ontology
|
GO:0006974 | cellular response to DNA damage stimulus | |
|
Gene Ontology
|
GO:0006950 | response to stress | |
|
Gene Ontology
|
GO:0006807 | nitrogen compound metabolic process | |
|
Gene Ontology
|
GO:0006725 | cellular aromatic compound metabolic process | |
|
Gene Ontology
|
GO:0006288 | base-excision repair, DNA ligation | |
|
Gene Ontology
|
GO:0006284 | base-excision repair | |
|
Gene Ontology
|
GO:0006281 | DNA repair | |
|
Gene Ontology
|
GO:0006266 | DNA ligation | |
|
Gene Ontology
|
GO:0006259 | DNA metabolic process | |
|
Gene Ontology
|
GO:0006139 | nucleobase-containing compound metabolic process | |
|
Gene Ontology
|
GO:0005886 | plasma membrane | |
|
Gene Ontology
|
GO:0005829 | cytosol | |
|
Gene Ontology
|
GO:0005737 | cytoplasm | |
|
Gene Ontology
|
GO:0005623 | obsolete cell | |
|
Gene Ontology
|
GO:0005622 | intracellular anatomical structure | |
|
Gene Ontology
|
GO:0005618 | cell wall | |
|
Gene Ontology
|
GO:0005575 | cellular_component | |
|
Gene Ontology
|
GO:0005488 | binding | |
|
Gene Ontology
|
GO:0003911 | DNA ligase (NAD+) activity | |
|
Gene Ontology
|
GO:0003909 | DNA ligase activity | |
|
Gene Ontology
|
GO:0003824 | catalytic activity | |
|
Gene Ontology
|
GO:0003674 | molecular_function | |
|
Gene Ontology
|
GO:0000287 | magnesium ion binding | |
|
Eggnog Protein
|
EP:ligA | ||
|
Eggnog Ortholog
|
EO:COG0272 | ||
|
Eggnog Description
|
ED:DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | ||
|
EC Number
|
EC:6.5.1.2 | DNA ligase (NAD+); polydeoxyribonucleotide synthase (NAD+); polynucleotide ligase (NAD+); DNA repair enzyme (ambiguous); DNA joinase (ambiguous); polynucleotide synthetase (nicotinamide adenine dinucleotide); deoxyribonucleic-joining enzyme (ambiguous); deoxyribonucleic ligase (ambiguous); deoxyribonucleic repair enzyme (ambiguous); deoxyribonucleic joinase (ambiguous); DNA ligase (ambiguous); deoxyribonucleate ligase (ambiguous); polynucleotide ligase (ambiguous); deoxyribonucleic acid ligase (ambiguous); polynucleotide synthetase (ambiguous); deoxyribonucleic acid joinase (ambiguous); DNA-joining enzyme (ambiguous); polynucleotide ligase (nicotinamide adenine dinucleotide); poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming, NMN-forming) |
| Pathway | Description |
|---|---|
| kornec03030 | DNA replication |
| kornec03410 | Base excision repair |
| kornec03420 | Nucleotide excision repair |
| kornec03430 | Mismatch repair |
Nucleotide sequence (GC-content: 70.7 %):
Protein sequence:
Located on scaffold FAM19038-p1-1_scf1
FAM19038-p1-1.1_001846
