| Type | Name | Description | Pathways |
|---|---|---|---|
|
Gene Code
|
recD | ||
|
Ortholog
|
N0.HOG0001265 | exodeoxyribonuclease V subunit alpha | |
|
KEGG gene
|
K03581 | recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] | kornec03440 |
|
Gene Ontology
|
GO:0071944 | cell periphery | |
|
Gene Ontology
|
GO:0044464 | obsolete cell part | |
|
Gene Ontology
|
GO:0044444 | obsolete cytoplasmic part | |
|
Gene Ontology
|
GO:0044424 | obsolete intracellular part | |
|
Gene Ontology
|
GO:0030312 | external encapsulating structure | |
|
Gene Ontology
|
GO:0016020 | membrane | |
|
Gene Ontology
|
GO:0005886 | plasma membrane | |
|
Gene Ontology
|
GO:0005829 | cytosol | |
|
Gene Ontology
|
GO:0005737 | cytoplasm | |
|
Gene Ontology
|
GO:0005623 | obsolete cell | |
|
Gene Ontology
|
GO:0005622 | intracellular anatomical structure | |
|
Gene Ontology
|
GO:0005618 | cell wall | |
|
Gene Ontology
|
GO:0005575 | cellular_component | |
|
Gene Product
|
exodeoxyribonuclease V subunit alpha | ||
|
Eggnog Protein
|
EP:recD | ||
|
Eggnog Ortholog
|
EO:COG0507 | ||
|
Eggnog Description
|
ED:A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD | ||
|
EC Number
|
EC:3.1.11.5 | exodeoxyribonuclease V; Escherichia coli exonuclease V; E. coli exonuclease V; gene recBC endoenzyme; RecBC deoxyribonuclease; gene recBC DNase; exonuclease V; gene recBCD enzymes |
| Pathway | Description |
|---|---|
| kornec03440 | Homologous recombination |
Nucleotide sequence (GC-content: 73.4 %):
Protein sequence:
Located on scaffold FAM19038-p1-1_scf1
FAM19038-p1-1.1_002110
