update range to 10000 bp
locus tag: FAM19038-p1-1.1_002141 genome: FAM19038-p1-1.1
species: Acidipropionibacterium jensenii taxid: 1749

Annotations

Type Name Description Pathways
KEGG reaction
 R08549 2-oxoglutarate:NAD+ 2-oxidoreductase (CoA-succinylating); 2-Oxoglutarate dehydrogenase complex; 2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+ kornec01100kornec01110kornec01120kornec01200
KEGG reaction
 R03316 3-Carboxy-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + Thiamin diphosphate kornec00020
KEGG reaction
 R01940 2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating); 2-Oxoadipate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine + CO2
KEGG reaction
 R01933 2-oxoadipate dehydrogenase complex; 2-Oxoadipate + CoA + NAD+ <=> Glutaryl-CoA + CO2 + NADH + H+ kornec00310kornec00380kornec01100kornec01110
KEGG reaction
 R00621 2-Oxoglutarate + Thiamin diphosphate <=> 3-Carboxy-1-hydroxypropyl-ThPP + CO2 kornec00020
Ortholog
 N0.HOG0001888 multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
Gene Product
 multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KEGG gene
 K01616 kgd; multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
KEGG gene
 K00164 OGDH, sucA; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] kornec00020kornec01100kornec01110kornec01120kornec01200
Gene Ontology
 GO:1990234 transferase complex
Gene Ontology
 GO:1990204 oxidoreductase complex
Gene Ontology
 GO:1902494 catalytic complex
Gene Ontology
 GO:0072350 tricarboxylic acid metabolic process
Gene Ontology
 GO:0071944 cell periphery
Gene Ontology
 GO:0071704 organic substance metabolic process
Gene Ontology
 GO:0055114 obsolete oxidation-reduction process
Gene Ontology
 GO:0051186 obsolete cofactor metabolic process
Gene Ontology
 GO:0050439 2-hydroxy-3-oxoadipate synthase activity
Gene Ontology
 GO:0046872 metal ion binding
Gene Ontology
 GO:0045333 cellular respiration
Gene Ontology
 GO:0045254 pyruvate dehydrogenase complex
Gene Ontology
 GO:0045252 oxoglutarate dehydrogenase complex
Gene Ontology
 GO:0045240 dihydrolipoyl dehydrogenase complex
Gene Ontology
 GO:0045239 tricarboxylic acid cycle enzyme complex
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0044444 obsolete cytoplasmic part
Gene Ontology
 GO:0044424 obsolete intracellular part
Gene Ontology
 GO:0044281 small molecule metabolic process
Gene Ontology
 GO:0044238 primary metabolic process
Gene Ontology
 GO:0044237 cellular metabolic process
Gene Ontology
 GO:0043648 dicarboxylic acid metabolic process
Gene Ontology
 GO:0043436 oxoacid metabolic process
Gene Ontology
 GO:0043169 cation binding
Gene Ontology
 GO:0043167 ion binding
Gene Ontology
 GO:0040007 growth
Gene Ontology
 GO:0032991 protein-containing complex
Gene Ontology
 GO:0030312 external encapsulating structure
Gene Ontology
 GO:0022900 electron transport chain
Gene Ontology
 GO:0019752 carboxylic acid metabolic process
Gene Ontology
 GO:0017144 -
Gene Ontology
 GO:0016999 antibiotic metabolic process
Gene Ontology
 GO:0016831 carboxy-lyase activity
Gene Ontology
 GO:0016830 carbon-carbon lyase activity
Gene Ontology
 GO:0016829 lyase activity
Gene Ontology
 GO:0016744 transketolase or transaldolase activity
Gene Ontology
 GO:0016740 transferase activity
Gene Ontology
 GO:0016491 oxidoreductase activity
Gene Ontology
 GO:0016020 membrane
Gene Ontology
 GO:0015980 energy derivation by oxidation of organic compounds
Gene Ontology
 GO:0009987 cellular process
Gene Ontology
 GO:0009060 aerobic respiration
Gene Ontology
 GO:0009055 electron transfer activity
Gene Ontology
 GO:0008683 2-oxoglutarate decarboxylase activity
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0006103 2-oxoglutarate metabolic process
Gene Ontology
 GO:0006101 citrate metabolic process
Gene Ontology
 GO:0006099 tricarboxylic acid cycle
Gene Ontology
 GO:0006091 generation of precursor metabolites and energy
Gene Ontology
 GO:0006082 organic acid metabolic process
Gene Ontology
 GO:0005886 plasma membrane
Gene Ontology
 GO:0005829 cytosol
Gene Ontology
 GO:0005737 cytoplasm
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005622 intracellular anatomical structure
Gene Ontology
 GO:0005618 cell wall
Gene Ontology
 GO:0005575 cellular_component
Gene Ontology
 GO:0005488 binding
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Gene Ontology
 GO:0000287 magnesium ion binding
Eggnog Protein
 EP:kgd
Eggnog Ortholog
 EO:COG0508
Eggnog Description
 ED:2-oxoglutarate dehydrogenase
EC Number
 EC:4.1.1.71 2-oxoglutarate decarboxylase; oxoglutarate decarboxylase; alpha-ketoglutarate decarboxylase; alpha-ketoglutaric decarboxylase; pre-2-oxoglutarate decarboxylase; 2-oxoglutarate carboxy-lyase
EC Number
 EC:1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring); 2-ketoglutarate dehydrogenase; 2-oxoglutarate dehydrogenase; 2-oxoglutarate: lipoate oxidoreductase; 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating); alpha-ketoglutarate dehydrogenase; alphaketoglutaric acid dehydrogenase; alpha-ketoglutaric dehydrogenase; alpha-oxoglutarate dehydrogenase; AKGDH; OGDC; ketoglutaric dehydrogenase; oxoglutarate decarboxylase (misleading); oxoglutarate dehydrogenase; oxoglutarate dehydrogenase (lipoamide) kornec00020kornec00310kornec00380kornec01100kornec01110kornec01120

Occurs in the following pathway maps:

Pathway Description
kornec00020 Citrate cycle (TCA cycle)
kornec00310 Lysine degradation
kornec00380 Tryptophan metabolism
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01120 Microbial metabolism in diverse environments
kornec01200 Carbon metabolism

Sequences

Nucleotide sequence (GC-content: 68.9 %):

GTGGCATCAGGTACTGCCGGACACACCAGCTCCCCGACCAGTGCGGAGTTCGGGGCCAATGACTGGCTGATAGACGAGATGCGCGAGCAGTTCCAACGGGACCCCGACTCGGTCGGTCCCGAGTGGGTCACCTTCTTCCAGGCCGAGGAGAGGACGTCGGCCCCCCGCAGCCCCGAGACGCCGCGAGCCCCGGAGTCCGCCGCCCCGGCCCCCCGCGAGGCAGACCCGGTCCCGCAACCGGACCCCACCGCGACGACGACCCCGCCCCAGCCCCGACGCGCTCAGCGGGAGGAACCCTCGGCTCCCCCGGCCGAACCGGCCCCGAGGGCCTCGGCCGCACCCTCCCCCGCCCCGTCAGCCCCGTCTCCCGCCCCGTCAACTCCGGCCGGCGCCCCGCACCGGGCGCCGGTGTCGGCGGACCAGCCGGTCCACGAGCCGCCCGCCGCAGCCCCGGCGGAGCCCCGCACCGAACGGTTGCGCGGCGCCCCGATGCGCACCGCCAAGAACATGGAGACCTCGCTGTCGATGCCGACAGCGACCTCGGTCCGCGACATCCCGATGAAGCTGGTCATCGAGAACCGCCTGATGATCAACCGTTTCCTGAGCCAGAACAAGGGCGGCAAGGTCTCCTTCACCCACATTCTCGGCTTCGCGATGGTCCGGGCCCTCAAGGACGTCCCGGCGATGAACAATGCCTACGCCGAGATCGACGGCAAGCCCCACATCATCGAGAACCCCTCGGTCAATCTCGGGCTGGCGATCGACGTGGTCGGTGCCGACGGCACCCGCAAGCTCGTGGTGCCGGCCATCAGAGCCGCCGAGGCGATGGACTTCAGCCAGTTCTGGGCGGCCTACGAGCAGATCGTCGCGAAAGGCCGCAAGAACACCCTGACCGTCGAGGACTTCAAGGGAGTCACCGCATCCCTCACCAACCCCGGCGGGATCGGCACCAACCACTCGGTGCCCCGTCTGATGCCCGGTCAGGGGATGATCCTGGGGATGGGATCGATCGACTACCCGGCCGGCTGGCAGGGCGGCAGCCCGACCCGGCTCGCCGAGCTCGGCATCTCGAAGGTGACCACCCTCACCTCGACCTACGACCACCGGATCATCCAGGGCGCCCAGTCCGGGGAGTTCCTGCGCCGCATCCACAAGCTGCTGCTGGGGGCCGACCGATTCTACGAGGAGATCTTCGAGTCCCTGCGGATCCCCTACGCGCCCGTCCAGTGGGCCCCCGACCGGATGGCCAGCCGCCCCGACCAGGTGAGCAAACAGGTCCGCGTCATCACCCTCATCGACGCCTGGCGGCAGTTCGGCCACATGTCGGCCGACCTGGACCCTCTCGAGTACAAGCCGCGGTACCACCACGACCTGATGCTCAACAGCCACGGCCTGACCCTGTGGGACCTCGACCGGTCCTTCCCGGTCAACAACTTCGGCGGCATGAAGCGCGCCAACCTCACGCTGCGCGAGATCCTGGAGATCCTGCGCGACTCCTACGCCTCCACGATGGGCATCGAGTACATGCACATCACCGACCACGAGCAGCGACGCTGGTTCCAGGACCGGTTCGAGCGGGTGCACACCCCGCTGTCGCGCGATGTGCACCTGCGGATCCTCGATCAGCTCACCGACGCCGAGGTCTTCGAGACCTTCCTGCAGACCAAGTACGTCGGCCAGAAGCGGTTCAGCCTGGAGGGCGGGGAGTCCGCCATCGTGCTGCTGGCTGCGATCTTCACCCAGGCGGCCGACCAGGGCCTCGACGAGGTGTGCATCGGCATGCCGCACCGCGGCCGGCTCAACGTTCTGGCCAACATCATCGGCAAGTCCTACGGGCAGATCTTCCGGGAGTTCGAGGGCAATGCCGAGCCCTCCAACTCCCAGGGATCGGGCGACGTCAAGTACCACCTCGGCGACGAGGGCCGGTTCACCGCCCCCTCGGGGCACAGCATCAAGGCCTCGGTGGCCGCGAACCCGAGTCACCTGGAGGCGGTCGACCCCGTTCTGGAGGGAATCTGCCGGGCCAAGCTCGACGTTCTGGCGGACTCCTCGCACTTCCCGGTGCTGCCCGTCCTGATGCACGGGGATGCCGCATTCGCCGGCCAGGGGGTGGTCTTCGAGACCCTCCAGATGAGCCAGCTGCGGCCCTACCGGACCGGCGGCACGATCCACGTGGTGGTCAACAACCAGGTGGGGTTCACCACCTCCCCGGCCGAGGGACGCACCTCCCAGTACGCCACCGGGGTGGCCAAGTCGATCGCGGCGCCGGTGATCCACGTCAACGGGGACGACCCGGCGGCCGTGGTGCGCGCCGCGCACATCGCCTTCGCCTACCGTCAGACCTTCCACGGCGACGTCGTCATCGACCTGTTCTGCTACCGGCGACGCGGTCACAACGAGGGCGACGACCCGAGCTTCACCCAGCCGCACATGTACGACCTCATCACCCAGAAGAGGTCGACCCGCAAGGTCTACACCGAGAGCCTGATCGGCCGCGGGGACATCACCCTGGAGGACGCCGACGCGGCGATGACGAGCTTCCGCAGGAAGCTCGAGACCGCCTTCGAGGAGGTTCGCAACGCCACCTCAAAGGCCCAGCCCTACGACTCGGTGCCCGACTACCCGCGCAAGAAGAACAAGGACCGGCCCACCGCCATCAGCGCCGAGATGATGGACCGGGTGGCCACCGCCCAGGAGGTGCTGCCCGCCAGCTTCACCCCGCACCCCAAGATCGCCCCCCAGCTGGCCAGGCGCGCCCGCGCGCTGCGCGGCCAGGGGCCGATCGACTGGGCCTCGGCCGAGATGCTCGCCCTGGGATCGCTGGTGGCCGAGGGGCTGCACGTGCGCCTCACCGGACAGGACTCGCGCCGGGGCACCTTCTCACAGCGGTTCGGCGCGATCGTCGACCGGGCCACCAACAAGCACTACGTGCCGGTGAACCACATCCCTGGAGCCAGGAGCCACCTGGACATCTACGACTCCCCCCTCAACGAGTACGCCTCGCTGGGCTTCGAGTACGGCTACTCGGTGGCCCGGCCCGACTCCCTGGTGCTCTGGGAGGCGCAGTTCGGCGACTTCGCCAATGTCGCCCAGACCATCATCGACGAGTTCATCGCCTCGGCCGGATCCAAGTGGGGGCAGAAGTCGGGGGTGGTCCTGCTCCTGCCGCACGGCTACGAGGGTCAGGGGCCCGACCACTCCTCGGCCCGTCTGGAGAGGTTCCTCTCGCTGTGCAGCGAGGAGGCGATGGCGGTCTGCCAGCCCTCGACGGCAGCCAGCTACTTCCACCTGCTGCGCTACCACGCCTACGTGAATCTGCACCGGCCGGTGGTCATCGCGACCCCGAAGTCGATGCTGCGCAACAAGGCGGCCGCCTCCACCGTGGAGGACTTCACCGAGGGTCACTGGCGTCCGGTGATCAGCGATGAGTCGATCTCCGATCCCTCGGGTGTCCGGCAGGTCATCCTGTGCACCGGGAAGGTGCGCTGGGAGCTGGTTCGGCGTCGCGAGCAGGCCCACCTGACCGAGAAGGTGGCGATCATCTCGATGGAGCGGCTCTACCCGCTGCCGACCCGGCAGCTGGTGGAGGCATTGGCCCCCTACCGCCACGTCGACGATGTCCGATGGGTTCAGGAGGAGCCGGCGAACCAGGGCCCGTGGCCGTTCATGCAGGCCCACCTCCGCGAGGCGGTGTCCTCCCTGGAGCCGGGCCTGCTGGACACCCTCACCGTGGTGGCGAGGCCTCCGTCGGCGGCCTCGTCGGTGGGCCAGCACAGCGTGCACATGGCCGAGGAGGAGGACCTGCTGACCGCTGCCCTGGCACAGCCCTGA

Protein sequence:

MASGTAGHTSSPTSAEFGANDWLIDEMREQFQRDPDSVGPEWVTFFQAEERTSAPRSPETPRAPESAAPAPREADPVPQPDPTATTTPPQPRRAQREEPSAPPAEPAPRASAAPSPAPSAPSPAPSTPAGAPHRAPVSADQPVHEPPAAAPAEPRTERLRGAPMRTAKNMETSLSMPTATSVRDIPMKLVIENRLMINRFLSQNKGGKVSFTHILGFAMVRALKDVPAMNNAYAEIDGKPHIIENPSVNLGLAIDVVGADGTRKLVVPAIRAAEAMDFSQFWAAYEQIVAKGRKNTLTVEDFKGVTASLTNPGGIGTNHSVPRLMPGQGMILGMGSIDYPAGWQGGSPTRLAELGISKVTTLTSTYDHRIIQGAQSGEFLRRIHKLLLGADRFYEEIFESLRIPYAPVQWAPDRMASRPDQVSKQVRVITLIDAWRQFGHMSADLDPLEYKPRYHHDLMLNSHGLTLWDLDRSFPVNNFGGMKRANLTLREILEILRDSYASTMGIEYMHITDHEQRRWFQDRFERVHTPLSRDVHLRILDQLTDAEVFETFLQTKYVGQKRFSLEGGESAIVLLAAIFTQAADQGLDEVCIGMPHRGRLNVLANIIGKSYGQIFREFEGNAEPSNSQGSGDVKYHLGDEGRFTAPSGHSIKASVAANPSHLEAVDPVLEGICRAKLDVLADSSHFPVLPVLMHGDAAFAGQGVVFETLQMSQLRPYRTGGTIHVVVNNQVGFTTSPAEGRTSQYATGVAKSIAAPVIHVNGDDPAAVVRAAHIAFAYRQTFHGDVVIDLFCYRRRGHNEGDDPSFTQPHMYDLITQKRSTRKVYTESLIGRGDITLEDADAAMTSFRRKLETAFEEVRNATSKAQPYDSVPDYPRKKNKDRPTAISAEMMDRVATAQEVLPASFTPHPKIAPQLARRARALRGQGPIDWASAEMLALGSLVAEGLHVRLTGQDSRRGTFSQRFGAIVDRATNKHYVPVNHIPGARSHLDIYDSPLNEYASLGFEYGYSVARPDSLVLWEAQFGDFANVAQTIIDEFIASAGSKWGQKSGVVLLLPHGYEGQGPDHSSARLERFLSLCSEEAMAVCQPSTAASYFHLLRYHAYVNLHRPVVIATPKSMLRNKAAASTVEDFTEGHWRPVISDESISDPSGVRQVILCTGKVRWELVRRREQAHLTEKVAIISMERLYPLPTRQLVEALAPYRHVDDVRWVQEEPANQGPWPFMQAHLREAVSSLEPGLLDTLTVVARPPSAASSVGQHSVHMAEEEDLLTAALAQP

GenBank Info

locus_tag - FAM19038-p1-1.1_002141
EC_number - 4.1.1.71
inference - COORDINATES: similar to AA sequence:RefSeq:WP_017935453.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
protein_id - extdb:FAM19038-p1-1.1_002141

Gene Locus

Located on scaffold FAM19038-p1-1_scf1

Cellular location expand

Responsible annotations:
SL-0041: GO:0005618 cell wall
SL-0229: GO:0005622 intracellular anatomical structure
SL-0086: GO:0005737 cytoplasm
SL-0091: GO:0005829 cytosol
SL-0039: GO:0005886 plasma membrane
SL-0162: GO:0016020 membrane
FAM19038-p1-1.1_002140
FAM19038-p1-1.1_002142