update range to 10000 bp
locus tag: FAM19038-p1-1.1_002314 genome: FAM19038-p1-1.1
species: Acidipropionibacterium jensenii taxid: 1749

Annotations

Type Name Description Pathways
KEGG reaction
 R04231 (R)-4'-phosphopantothenate:L-cysteine ligase; CTP + D-4'-Phosphopantothenate + L-Cysteine <=> CMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine kornec00770kornec01100kornec01240
KEGG reaction
 R03269 N-[(R)-4'-Phosphopantothenoyl]-L-cysteine carboxy-lyase; (R)-4'-Phosphopantothenoyl-L-cysteine <=> Pantetheine 4'-phosphate + CO2 kornec00770kornec01100kornec01240
Ortholog
 N0.HOG0001084 phosphopantothenoylcysteine decarboxylase
KEGG gene
 K13038 coaBC, dfp; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] kornec00770kornec01100kornec01240
Gene Ontology
 GO:1901576 organic substance biosynthetic process
Gene Ontology
 GO:1901566 organonitrogen compound biosynthetic process
Gene Ontology
 GO:1901564 organonitrogen compound metabolic process
Gene Ontology
 GO:1901362 organic cyclic compound biosynthetic process
Gene Ontology
 GO:1901360 organic cyclic compound metabolic process
Gene Ontology
 GO:1901293 nucleoside phosphate biosynthetic process
Gene Ontology
 GO:1901137 carbohydrate derivative biosynthetic process
Gene Ontology
 GO:1901135 carbohydrate derivative metabolic process
Gene Ontology
 GO:0090407 organophosphate biosynthetic process
Gene Ontology
 GO:0072522 purine-containing compound biosynthetic process
Gene Ontology
 GO:0072521 purine-containing compound metabolic process
Gene Ontology
 GO:0071944 cell periphery
Gene Ontology
 GO:0071704 organic substance metabolic process
Gene Ontology
 GO:0055086 nucleobase-containing small molecule metabolic process
Gene Ontology
 GO:0051188 obsolete cofactor biosynthetic process
Gene Ontology
 GO:0051186 obsolete cofactor metabolic process
Gene Ontology
 GO:0046483 heterocycle metabolic process
Gene Ontology
 GO:0046390 ribose phosphate biosynthetic process
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0044281 small molecule metabolic process
Gene Ontology
 GO:0044271 cellular nitrogen compound biosynthetic process
Gene Ontology
 GO:0044249 cellular biosynthetic process
Gene Ontology
 GO:0044238 primary metabolic process
Gene Ontology
 GO:0044237 cellular metabolic process
Gene Ontology
 GO:0040007 growth
Gene Ontology
 GO:0034654 nucleobase-containing compound biosynthetic process
Gene Ontology
 GO:0034641 cellular nitrogen compound metabolic process
Gene Ontology
 GO:0034033 purine nucleoside bisphosphate biosynthetic process
Gene Ontology
 GO:0034032 purine nucleoside bisphosphate metabolic process
Gene Ontology
 GO:0034030 ribonucleoside bisphosphate biosynthetic process
Gene Ontology
 GO:0033875 ribonucleoside bisphosphate metabolic process
Gene Ontology
 GO:0033866 nucleoside bisphosphate biosynthetic process
Gene Ontology
 GO:0033865 nucleoside bisphosphate metabolic process
Gene Ontology
 GO:0019693 ribose phosphate metabolic process
Gene Ontology
 GO:0019637 organophosphate metabolic process
Gene Ontology
 GO:0019438 aromatic compound biosynthetic process
Gene Ontology
 GO:0018130 heterocycle biosynthetic process
Gene Ontology
 GO:0016831 carboxy-lyase activity
Gene Ontology
 GO:0016830 carbon-carbon lyase activity
Gene Ontology
 GO:0016829 lyase activity
Gene Ontology
 GO:0016020 membrane
Gene Ontology
 GO:0015937 coenzyme A biosynthetic process
Gene Ontology
 GO:0015936 coenzyme A metabolic process
Gene Ontology
 GO:0009987 cellular process
Gene Ontology
 GO:0009260 ribonucleotide biosynthetic process
Gene Ontology
 GO:0009259 ribonucleotide metabolic process
Gene Ontology
 GO:0009165 nucleotide biosynthetic process
Gene Ontology
 GO:0009152 purine ribonucleotide biosynthetic process
Gene Ontology
 GO:0009150 purine ribonucleotide metabolic process
Gene Ontology
 GO:0009117 nucleotide metabolic process
Gene Ontology
 GO:0009108 obsolete coenzyme biosynthetic process
Gene Ontology
 GO:0009058 biosynthetic process
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0006807 nitrogen compound metabolic process
Gene Ontology
 GO:0006796 phosphate-containing compound metabolic process
Gene Ontology
 GO:0006793 phosphorus metabolic process
Gene Ontology
 GO:0006753 nucleoside phosphate metabolic process
Gene Ontology
 GO:0006732 obsolete coenzyme metabolic process
Gene Ontology
 GO:0006725 cellular aromatic compound metabolic process
Gene Ontology
 GO:0006164 purine nucleotide biosynthetic process
Gene Ontology
 GO:0006163 purine nucleotide metabolic process
Gene Ontology
 GO:0006139 nucleobase-containing compound metabolic process
Gene Ontology
 GO:0005886 plasma membrane
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005575 cellular_component
Gene Ontology
 GO:0004633 phosphopantothenoylcysteine decarboxylase activity
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Eggnog Protein
 EP:coaBC
Eggnog Ortholog
 EO:COG0452
Eggnog Description
 ED:Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine
EC Number
 EC:6.3.2.5 phosphopantothenate---cysteine ligase (CTP); phosphopantothenoylcysteine synthetase (ambiguous); phosphopantothenate---cysteine ligase (ambiguous) kornec00770kornec01100
EC Number
 EC:4.1.1.36 phosphopantothenoylcysteine decarboxylase; 4-phosphopantotheoylcysteine decarboxylase; 4-phosphopantothenoyl-L-cysteine decarboxylase; PPC-decarboxylase; N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase kornec00770kornec01100
Gene Code
 coaBC
Gene Product
 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC

Occurs in the following pathway maps:

Pathway Description
kornec00770 Pantothenate and CoA biosynthesis
kornec01100 Metabolic pathways
kornec01240 Biosynthesis of cofactors

Sequences

Nucleotide sequence (GC-content: 71.8 %):

GTGTCCACGGTTGTCCTGGGGGTGGGCGGCGGCATCGCCGCCTACAAGGCCTGCTACCTCGTGCGGCGGTTGGCCGAGGCCGGTCACCGGGTGCACGTCATTCCCACCGAGGCGGCCCTTCAGTTCGTCGGGCGTCCGACCTGGGAGGCCCTGTCGGGCAATCCGGTTCACACCACCGTCTTCGACGATGTCCCCGGCGTCGAGCACGTCCGGCTGGGGGAGCAGGCCGATCTGGTGATCGTGGCCCCGGCCACCGCCGACCTGGTGTCCAGGATCGCCGCCGGAGCGGCCGATGACCTGCTCACCGCCACCGTTCTCGCCACCCGGGCCCCGGTCCTGGTGGCCCCGGCGATGCACACCGCGATGTGGCAGAACCCGGCCACCCGCGACAACGTGGCCACCCTGCGACGCCGCGGAGTCGTCGTCAAGGACCCCGCCGACGGTCGTCTCACCGGGCCCGACTCCGGACCCGGGCGCCTTCCCGAACCCGATGAACTGGCCGAGCTGGCCGCTCTGCTGCTGGCCGATCCCGGGGTCGTCGGCTCCCTGGCCGCCCAGGACCTGACCGGACGCCGGGTCGTCATCTCGGCCGGTGGGACCCGCGAGGCCCTGGACCCGGTGCGATACCTCGGCAACTCCTCCTCGGGGAGGATGGGCACCGCCCTGGCGATGCTGGCCGTCGCCCGTGGGGCCGAGGTGACCCTGGTCAGCGCGCACCTGGAGGTGCCGGTGCCCTCCTGCCTCCATCAGATCCCGGTCTCCAGCACCGAGGACCTGTCCGAGGTGATGGGGACGCTGGCCCCGAGTGCCGATGTCATCGTGATGGCGGTCGCCGCCGCCGACTTCGCCCCGGTATCCAGCGCGCAGGTCAAGATCAAGAAGCACGAGGGATCGGACGCCGTCGGTGCCGGGACCAGGATCGACCTGGTCCAGACCCCCGATGTGCTGGCCGCCCTGGCCGCCTCGAGACGACCCGGCCAGGTCATCGTGGGGTTCGCCGCCGAGACCGCCCCCGATCGCGCCGAGTTGCTGGAGCTGGCCGCGGCGAAGCTGCGCCGCAAGGCCTGTGACCTGCTGGTCGTCAACGATGTGAGCGCCGGGAAGGTCTTCGGTAAGGTCGACACCGACGTCACCGTGGTCCGCCAGCAGGGACCCGGTCGACGCGTCCAGGGCCCCAAGATGATGGCCGCCCAGGCCATCCTCGACGAGGTCCGCTCGCTGCTGGCTCCCGCATCGGGCACCCCGGAACCTGTTCCGGCGTCCTGA

Protein sequence:

MSTVVLGVGGGIAAYKACYLVRRLAEAGHRVHVIPTEAALQFVGRPTWEALSGNPVHTTVFDDVPGVEHVRLGEQADLVIVAPATADLVSRIAAGAADDLLTATVLATRAPVLVAPAMHTAMWQNPATRDNVATLRRRGVVVKDPADGRLTGPDSGPGRLPEPDELAELAALLLADPGVVGSLAAQDLTGRRVVISAGGTREALDPVRYLGNSSSGRMGTALAMLAVARGAEVTLVSAHLEVPVPSCLHQIPVSSTEDLSEVMGTLAPSADVIVMAVAAADFAPVSSAQVKIKKHEGSDAVGAGTRIDLVQTPDVLAALAASRRPGQVIVGFAAETAPDRAELLELAAAKLRRKACDLLVVNDVSAGKVFGKVDTDVTVVRQQGPGRRVQGPKMMAAQAILDEVRSLLAPASGTPEPVPAS

GenBank Info

gene - coaBC
locus_tag - FAM19038-p1-1.1_002314
EC_number - 4.1.1.36 --AND-- 6.3.2.5
inference - COORDINATES: similar to AA sequence:RefSeq:WP_015070475.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
protein_id - extdb:FAM19038-p1-1.1_002314

Gene Locus

Located on scaffold FAM19038-p1-1_scf1

Cellular location expand

Responsible annotations:
SL-0039: GO:0005886 plasma membrane
SL-0162: GO:0016020 membrane
FAM19038-p1-1.1_002313
FAM19038-p1-1.1_002315