Annotations

Type Name Description Pathways
Gene Code
ruvC
Ortholog
N0.HOG0002295 crossover junction endodeoxyribonuclease RuvC
KEGG gene
K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] kornec03440
Gene Ontology
GO:1901576 organic substance biosynthetic process
Gene Ontology
GO:1901360 organic cyclic compound metabolic process
Gene Ontology
GO:0140097 catalytic activity, acting on DNA
Gene Ontology
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Gene Ontology
GO:0090304 nucleic acid metabolic process
Gene Ontology
GO:0071932 replication fork reversal
Gene Ontology
GO:0071704 organic substance metabolic process
Gene Ontology
GO:0051716 cellular response to stimulus
Gene Ontology
GO:0050896 response to stimulus
Gene Ontology
GO:0048476 Holliday junction resolvase complex
Gene Ontology
GO:0046483 heterocycle metabolic process
Gene Ontology
GO:0045005 DNA-templated DNA replication maintenance of fidelity
Gene Ontology
GO:0044464 obsolete cell part
Gene Ontology
GO:0044424 obsolete intracellular part
Gene Ontology
GO:0044260 cellular macromolecule metabolic process
Gene Ontology
GO:0044249 cellular biosynthetic process
Gene Ontology
GO:0044238 primary metabolic process
Gene Ontology
GO:0044237 cellular metabolic process
Gene Ontology
GO:0043170 macromolecule metabolic process
Gene Ontology
GO:0034645 cellular macromolecule biosynthetic process
Gene Ontology
GO:0034641 cellular nitrogen compound metabolic process
Gene Ontology
GO:0033554 cellular response to stress
Gene Ontology
GO:0032991 protein-containing complex
Gene Ontology
GO:0031297 replication fork processing
Gene Ontology
GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
Gene Ontology
GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters
Gene Ontology
GO:0016788 hydrolase activity, acting on ester bonds
Gene Ontology
GO:0016787 hydrolase activity
Gene Ontology
GO:0009987 cellular process
Gene Ontology
GO:0009059 macromolecule biosynthetic process
Gene Ontology
GO:0009058 biosynthetic process
Gene Ontology
GO:0008821 crossover junction endodeoxyribonuclease activity
Gene Ontology
GO:0008152 metabolic process
Gene Ontology
GO:0008150 biological_process
Gene Ontology
GO:0006974 cellular response to DNA damage stimulus
Gene Ontology
GO:0006950 response to stress
Gene Ontology
GO:0006807 nitrogen compound metabolic process
Gene Ontology
GO:0006725 cellular aromatic compound metabolic process
Gene Ontology
GO:0006310 DNA recombination
Gene Ontology
GO:0006281 DNA repair
Gene Ontology
GO:0006261 DNA-templated DNA replication
Gene Ontology
GO:0006260 DNA replication
Gene Ontology
GO:0006259 DNA metabolic process
Gene Ontology
GO:0006139 nucleobase-containing compound metabolic process
Gene Ontology
GO:0005623 obsolete cell
Gene Ontology
GO:0005622 intracellular anatomical structure
Gene Ontology
GO:0005575 cellular_component
Gene Ontology
GO:0004536 deoxyribonuclease activity
Gene Ontology
GO:0004520 endodeoxyribonuclease activity
Gene Ontology
GO:0004519 endonuclease activity
Gene Ontology
GO:0004518 nuclease activity
Gene Ontology
GO:0003824 catalytic activity
Gene Ontology
GO:0003674 molecular_function
Gene Ontology
GO:0000725 recombinational repair
Eggnog Protein
EP:ruvC
Eggnog Ortholog
EO:COG0817
Eggnog Description
ED:Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EC Number
EC:3.1.22.4 Transferred to 3.1.21.10
Gene Product
crossover junction endodeoxyribonuclease RuvC

Occurs in the following pathway maps:

Pathway Description
kornec03440 Homologous recombination

Sequences

Nucleotide sequence (GC-content: 72.5 %):

ATGGGGGTCGATCCCGGCCTGACCCGGTGCGGGGTGGCCCTGGTCGAGGGCGGTTACGGCCGCCAGCTGAGACTGGTGGCCGTCGGCGTCATCCGCACCCCGGCTGACCAGGACACCTCCCGCCGGTTGCTGCACATCCACGACGAGCTGGAGGAGTGGTGCACCACCTACCGCCCCGACCAGGTGGCCATCGAGAGGGTCTTCGCCCAGCACAACAGGTCCACCGTGACCGGCACCGCACAGGCCGCCGGGCTGGCGATGGTGGTGGGGGCCCGGCACGGACTTCCGGTCGCCCTGCACACCCCCAGTGAGGTCAAGGCGGCGATTTCCGGGTCGGGTCGGGCCGACAAGTCCCAGGTGGGGCTGATGGTGGCCCGTGTCCTGCACCTGGACAAGGCCCCCCGACCCGCCGACGCCGCCGACGCGGTGGCCCTGGCGATCTGCCAGATCTGGCGCGGCGGGGCCGACCAGCGTCTGCAGGCCGCGGCCGAGGCCCAGCGGGCCGTCACCGGGCGCAGAGCCCGTTCATGGAAGGATCTGGCACGTTGA

Protein sequence:

MGVDPGLTRCGVALVEGGYGRQLRLVAVGVIRTPADQDTSRRLLHIHDELEEWCTTYRPDQVAIERVFAQHNRSTVTGTAQAAGLAMVVGARHGLPVALHTPSEVKAAISGSGRADKSQVGLMVARVLHLDKAPRPADAADAVALAICQIWRGGADQRLQAAAEAQRAVTGRRARSWKDLAR

GenBank Info

gene - ruvC
locus_tag - FAM19038-p1-1.1_002351
EC_number - 3.1.22.4
inference - COORDINATES: similar to AA sequence:RefSeq:WP_004811341.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - crossover junction endodeoxyribonuclease RuvC
protein_id - extdb:FAM19038-p1-1.1_002351

Gene Locus

Located on scaffold FAM19038-p1-1_scf1


Cellular location expand

Responsible annotations:
SL-0229: GO:0005622 intracellular anatomical structure

FAM19038-p1-1.1_002350
FAM19038-p1-1.1_002352