update range to 10000 bp
locus tag: FAM19038-p1-1.1_002407 genome: FAM19038-p1-1.1
species: Acidipropionibacterium jensenii taxid: 1749

Annotations

Type Name Description Pathways
KEGG reaction
 R01900 isocitrate hydro-lyase (cis-aconitate-forming); Isocitrate <=> cis-Aconitate + H2O kornec00020kornec00630kornec00720kornec01100kornec01110kornec01120kornec01210
KEGG reaction
 R01325 citrate hydro-lyase (cis-aconitate-forming); Citrate <=> cis-Aconitate + H2O kornec00020kornec00630kornec00720kornec01100kornec01110kornec01120kornec01210
KEGG reaction
 R01324 citrate hydroxymutase; Citrate <=> Isocitrate kornec01100kornec01200kornec01210kornec01230
Ortholog
 N0.HOG0001939 aconitate hydratase AcnA
KEGG gene
 K01681 ACO, acnA; aconitate hydratase [EC:4.2.1.3] kornec00020kornec00630kornec00720kornec01100kornec01110kornec01120kornec01200kornec01210kornec01230
Gene Ontology
 GO:1901363 heterocyclic compound binding
Gene Ontology
 GO:0097159 organic cyclic compound binding
Gene Ontology
 GO:0072350 tricarboxylic acid metabolic process
Gene Ontology
 GO:0071944 cell periphery
Gene Ontology
 GO:0071704 organic substance metabolic process
Gene Ontology
 GO:0055114 obsolete oxidation-reduction process
Gene Ontology
 GO:0051540 metal cluster binding
Gene Ontology
 GO:0051539 4 iron, 4 sulfur cluster binding
Gene Ontology
 GO:0051538 3 iron, 4 sulfur cluster binding
Gene Ontology
 GO:0051536 iron-sulfur cluster binding
Gene Ontology
 GO:0050896 response to stimulus
Gene Ontology
 GO:0048037 obsolete cofactor binding
Gene Ontology
 GO:0047456 2-methylisocitrate dehydratase activity
Gene Ontology
 GO:0046914 transition metal ion binding
Gene Ontology
 GO:0046872 metal ion binding
Gene Ontology
 GO:0046459 short-chain fatty acid metabolic process
Gene Ontology
 GO:0045333 cellular respiration
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0044444 obsolete cytoplasmic part
Gene Ontology
 GO:0044424 obsolete intracellular part
Gene Ontology
 GO:0044281 small molecule metabolic process
Gene Ontology
 GO:0044255 cellular lipid metabolic process
Gene Ontology
 GO:0044238 primary metabolic process
Gene Ontology
 GO:0044237 cellular metabolic process
Gene Ontology
 GO:0043436 oxoacid metabolic process
Gene Ontology
 GO:0043231 intracellular membrane-bounded organelle
Gene Ontology
 GO:0043229 intracellular organelle
Gene Ontology
 GO:0043227 membrane-bounded organelle
Gene Ontology
 GO:0043226 organelle
Gene Ontology
 GO:0043169 cation binding
Gene Ontology
 GO:0043167 ion binding
Gene Ontology
 GO:0042221 response to chemical
Gene Ontology
 GO:0040007 growth
Gene Ontology
 GO:0032787 monocarboxylic acid metabolic process
Gene Ontology
 GO:0030350 iron-responsive element binding
Gene Ontology
 GO:0030312 external encapsulating structure
Gene Ontology
 GO:0019752 carboxylic acid metabolic process
Gene Ontology
 GO:0019679 propionate metabolic process, methylcitrate cycle
Gene Ontology
 GO:0019541 propionate metabolic process
Gene Ontology
 GO:0017144 -
Gene Ontology
 GO:0016999 antibiotic metabolic process
Gene Ontology
 GO:0016836 hydro-lyase activity
Gene Ontology
 GO:0016835 carbon-oxygen lyase activity
Gene Ontology
 GO:0016829 lyase activity
Gene Ontology
 GO:0016020 membrane
Gene Ontology
 GO:0015980 energy derivation by oxidation of organic compounds
Gene Ontology
 GO:0010039 response to iron ion
Gene Ontology
 GO:0010038 response to metal ion
Gene Ontology
 GO:0010035 response to inorganic substance
Gene Ontology
 GO:0009987 cellular process
Gene Ontology
 GO:0009060 aerobic respiration
Gene Ontology
 GO:0008198 ferrous iron binding
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0006631 fatty acid metabolic process
Gene Ontology
 GO:0006629 lipid metabolic process
Gene Ontology
 GO:0006101 citrate metabolic process
Gene Ontology
 GO:0006099 tricarboxylic acid cycle
Gene Ontology
 GO:0006091 generation of precursor metabolites and energy
Gene Ontology
 GO:0006082 organic acid metabolic process
Gene Ontology
 GO:0005886 plasma membrane
Gene Ontology
 GO:0005829 cytosol
Gene Ontology
 GO:0005739 mitochondrion
Gene Ontology
 GO:0005737 cytoplasm
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005622 intracellular anatomical structure
Gene Ontology
 GO:0005618 cell wall
Gene Ontology
 GO:0005576 extracellular region
Gene Ontology
 GO:0005575 cellular_component
Gene Ontology
 GO:0005506 iron ion binding
Gene Ontology
 GO:0005488 binding
Gene Ontology
 GO:0003994 aconitate hydratase activity
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003730 mRNA 3'-UTR binding
Gene Ontology
 GO:0003729 mRNA binding
Gene Ontology
 GO:0003723 RNA binding
Gene Ontology
 GO:0003676 nucleic acid binding
Gene Ontology
 GO:0003674 molecular_function
Eggnog Protein
 EP:acnA
Eggnog Ortholog
 EO:COG1048
Eggnog Description
 ED:Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EC Number
 EC:4.2.1.3 aconitate hydratase; cis-aconitase; aconitase; AcnB; 2-methylaconitate hydratase; citrate(isocitrate) hydro-lyase kornec00020kornec00630kornec00720kornec01100kornec01110kornec01120
Gene Product
 aconitate hydratase AcnA
Gene Code
 acnA

Occurs in the following pathway maps:

Pathway Description
kornec00020 Citrate cycle (TCA cycle)
kornec00630 Glyoxylate and dicarboxylate metabolism
kornec00720 Carbon fixation pathways in prokaryotes
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01120 Microbial metabolism in diverse environments
kornec01200 Carbon metabolism
kornec01210 2-Oxocarboxylic acid metabolism
kornec01230 Biosynthesis of amino acids

Sequences

Nucleotide sequence (GC-content: 68.8 %):

ATGAGCATCAATAGTTTCGGCGCGAGAAGAACCCTCGAGGTCGATGGCCAGTCGTACCAGATCTACGGGGTGGACGCCGTCGAGGGTTCGGCGGACCTGCCCTACAGCCTCAAGGTGCTCCTGGAGAACCTGCTGCGCACCGAGGACGGCGCCAACATCACCACCGACCAGATCTCCTCGCTGGGCCACTGGGACCCCGAGGCCCAGCCCTCCCACGAGATCCAGTTCACCCCGGCCAGGGTGATCATGCAGGACTTCACCGGCGTCCCCTGCATCGTGGACCTGGCCACCATGCGCGAGGCGGTCGCCGATCTGGGTGGGAACCCCGAGCAGGTCAATCCGCTGTCTCCGGCCGAGATGGTCATCGACCACTCCGTTATCGTCGACAGCTTCGGCACCCCCAGGGCCTTCGAGTTCAACCAGGAGATGGAGTACCAGCGCAACCGCGAGCGCTACCAGTTCCTGCGCTGGGGCCAGGGCGCCTTCGAGAACTTCCGGGTCGTCCCGCCGGGCACCGGCATCGTCCACCAGGTCAACATCGAGCACCTCGCCCGGGTGACCTTCGTCGGCGAGGAGGACGGCCGGAAGGTCGCCTATCCGGACACCTGCGTGGGCACCGACTCCCACACCACGATGGTCAACGGACTCGGCGTGGTGGGCTGGGGGGTCGGCGGGATCGAGGCCGAGGCCGCAATGCTGGGCCAGCCGGTCTCGATGCTGGTGCCCCGGGTGGTCGGCTTCAAGCTCCACGGCGCCCTCGCCGAGGGGGTCACCGCCACCGACCTGGTGCTCACCATCACCCAGATGCTGCGCGAGCACAAGGTGGTCGGCAAGTTCGTCGAGTTCTACGGGCCGGGCGTGGCGGCCGTTCCGCTGGCCAACCGGGCCACCCTGGGCAATATGAGCCCCGAGTACGGCTCGACCATCGCCGTCTTCCCGATCGACCAGGTGACCCTGGACTACCTGCGCCTCACCGGACGCCCCGAGCACCAGATCGCCCTGGTGGAGGCCTACGCCCGGGCCCAGGGGATGTGGCACGACCCCGACCACGAGCCGCGTTACTCCGAGTACCTGGAGCTGGACCTGTCGACCGTCGAGCCCTCCCTGGCCGGACCCAAGCGCCCCCAGGACCGGATCCCGCTGGCCGGCTCCAAGCAGGCCTTCGAGAAGGTAGTGCCGCGCTACTCCTCCCAGCCCGACATCACGGTCCCGGTCACCCTCTCCGACGACCGCTCCTTCGACCTGCGCAACGGCGCGGTGAGCGTGGCGGCGATCACCTCCTGCACCAACACCTCCAACCCGAGCGTGATGATCTCCGCCGGGCTGGTGGCCCGCAAGGCCCGCGCCCTGGGGCTGAGCCCCAAGCCGTGGGTCAAGACCTCCCTGGCGCCGGGCTCCCAGGTGGTCACCGACTACCTGGACCGGTCCGGACTGACCTCCGACCTGGACGCCCTGGGCTTCGACCTGGTCGGCTACGGGTGCACCACCTGCATCGGGAACACCGGCCCGCTGATCCCGGAGATCTCGGCGGCGGTCAACGAGAACGACATGGCCGTCACCGCGGTGCTGTCGGGCAACCGCAACTTCGAGGGCAGGATCAGCCCCGACGTCAAGATGAACTACCTCGCCTCGCCGCCCCTGGTGGTGGTCTACGCCCTGGCCGGCACGATGGACATCGATCTGGCCAACGAGCCGATCGGCACCGCCTCCGACGGCACCGATGTGTTCATGAAGGACGTCTGGCCCTCGGCCGAGGAGATCGAGCAGATCGTCGGTTCGGCGATCTCCGCCGACATGTACACCAGCCGCTACGCCGACGTCTTCGAGGGAGGTCCGCGCTGGAAGTCCCTGGAGACCCCCGACGGCAAGACCTTCGCCTGGGACCCGGAGTCGACCTATGTGCGCAAGCTGCCGATCTTCGACGGGATGCCCGCCGAGCCGCAGCCGGTCGGCGACATCACCGGGGCGAGGGTGCTGCTGAAGCTCGGCGACTCGGTGACCACCGACCACATCTCCCCGGCCGGGGCCATCAAGGCCGACTCGCCGGCCGGGCGCTGGCTGGCCGAGCGCGGGATCGCCCGCAAGGACTTCAACTCCTACGGCTCGCGGCGCGGCAACCACGAGGTGATGATGCGCGGCACCTTCGCCAACATCAGGCTGCGCAACCAGCTGGCACCGGGGACCGAGGGCGGATTCACCCGCGATCTCACCGTCGACGGCGGACCGGTCACCACCGTCTTCGACGCCTCCCAGCACTACCAGGCCGCCGGCATCCCGCTGGTCGTCCTGGGCGGCAAGGAGTACGGCTCGGGATCCTCCCGGGACTGGGCGGCCAAGGGCACGATGCTGCTCGGCGTCCGGGCGGTCATCACCGAGTCCTATGAGCGGATCCACCGCTCCAACCTCATCGGGATGGGGGTCCTGCCGCTGCAGTTCCCCGAGGGCTCCAGCGCCGACTCGCTGGGTCTGAACGGCACCGAGGTCTTCGAGATCACCGGCGTCGACGCCATCAACGAGACGATCCCCGAGACGGTCCACGTGCGGGCCACCGCGCCGGCCGACGCCCCTGCCCGGACCGTCGAGTTCGACGCCGTGGTGCGCATCGACACGCCAGGGGAGCGGGAGTACTACCTCAACGGCGGCATCCTGCAGTACGTGCTGCGGCACATGGCGTCGCGCTGA

Protein sequence:

MSINSFGARRTLEVDGQSYQIYGVDAVEGSADLPYSLKVLLENLLRTEDGANITTDQISSLGHWDPEAQPSHEIQFTPARVIMQDFTGVPCIVDLATMREAVADLGGNPEQVNPLSPAEMVIDHSVIVDSFGTPRAFEFNQEMEYQRNRERYQFLRWGQGAFENFRVVPPGTGIVHQVNIEHLARVTFVGEEDGRKVAYPDTCVGTDSHTTMVNGLGVVGWGVGGIEAEAAMLGQPVSMLVPRVVGFKLHGALAEGVTATDLVLTITQMLREHKVVGKFVEFYGPGVAAVPLANRATLGNMSPEYGSTIAVFPIDQVTLDYLRLTGRPEHQIALVEAYARAQGMWHDPDHEPRYSEYLELDLSTVEPSLAGPKRPQDRIPLAGSKQAFEKVVPRYSSQPDITVPVTLSDDRSFDLRNGAVSVAAITSCTNTSNPSVMISAGLVARKARALGLSPKPWVKTSLAPGSQVVTDYLDRSGLTSDLDALGFDLVGYGCTTCIGNTGPLIPEISAAVNENDMAVTAVLSGNRNFEGRISPDVKMNYLASPPLVVVYALAGTMDIDLANEPIGTASDGTDVFMKDVWPSAEEIEQIVGSAISADMYTSRYADVFEGGPRWKSLETPDGKTFAWDPESTYVRKLPIFDGMPAEPQPVGDITGARVLLKLGDSVTTDHISPAGAIKADSPAGRWLAERGIARKDFNSYGSRRGNHEVMMRGTFANIRLRNQLAPGTEGGFTRDLTVDGGPVTTVFDASQHYQAAGIPLVVLGGKEYGSGSSRDWAAKGTMLLGVRAVITESYERIHRSNLIGMGVLPLQFPEGSSADSLGLNGTEVFEITGVDAINETIPETVHVRATAPADAPARTVEFDAVVRIDTPGEREYYLNGGILQYVLRHMASR

GenBank Info

gene - acnA
locus_tag - FAM19038-p1-1.1_002407
EC_number - 4.2.1.3
inference - COORDINATES: similar to AA sequence:RefSeq:WP_013863151.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - aconitate hydratase AcnA
protein_id - extdb:FAM19038-p1-1.1_002407

Gene Locus

Located on scaffold FAM19038-p1-1_scf1

Cellular location expand

Responsible annotations:
SL-0243: GO:0005576 extracellular region
SL-0041: GO:0005618 cell wall
SL-0229: GO:0005622 intracellular anatomical structure
SL-0086: GO:0005737 cytoplasm
SL-0173: GO:0005739 mitochondrion
SL-0091: GO:0005829 cytosol
SL-0039: GO:0005886 plasma membrane
SL-0162: GO:0016020 membrane
SL-0166: GO:0043231 intracellular membrane-bounded organelle
FAM19038-p1-1.1_002406
FAM19038-p1-1.1_002408