update range to 10000 bp
locus tag: FAM19038-p1-1.1_002439 genome: FAM19038-p1-1.1
species: Acidipropionibacterium jensenii taxid: 1749

Annotations

Type Name Description Pathways
Gene Product
 vitamin B12-dependent ribonucleotide reductase
KEGG reaction
 R02024 2'-deoxycytidine diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dCDP + Thioredoxin disulfide + H2O <=> Thioredoxin + CDP kornec00240kornec01100
KEGG reaction
 R02019 2'-deoxyguanosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dGDP + Thioredoxin disulfide + H2O <=> GDP + Thioredoxin kornec00230kornec01100
KEGG reaction
 R02018 2'-deoxyuridine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dUDP + Thioredoxin disulfide + H2O <=> Thioredoxin + UDP kornec00240kornec01100
KEGG reaction
 R02017 2'-deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dADP + Thioredoxin disulfide + H2O <=> Thioredoxin + ADP kornec00230kornec01100
Ortholog
 N0.HOG0002068 vitamin B12-dependent ribonucleotide reductase
KEGG gene
 K00525 E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] kornec00230kornec00240kornec01100
Gene Ontology
 GO:0071944 cell periphery
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0044444 obsolete cytoplasmic part
Gene Ontology
 GO:0044424 obsolete intracellular part
Gene Ontology
 GO:0030312 external encapsulating structure
Gene Ontology
 GO:0016020 membrane
Gene Ontology
 GO:0005886 plasma membrane
Gene Ontology
 GO:0005829 cytosol
Gene Ontology
 GO:0005737 cytoplasm
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005622 intracellular anatomical structure
Gene Ontology
 GO:0005618 cell wall
Gene Ontology
 GO:0005575 cellular_component
Eggnog Protein
 EP:nrdJ
Eggnog Ortholog
 EO:COG0209
Eggnog Description
 ED:Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
EC Number
 EC:1.17.4.1 ribonucleoside-diphosphate reductase; ribonucleotide reductase (ambiguous); CDP reductase; ribonucleoside diphosphate reductase; UDP reductase; ADP reductase; nucleoside diphosphate reductase; ribonucleoside 5'-diphosphate reductase; ribonucleotide diphosphate reductase; 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; RR; nrdB (gene name); nrdF (gene name); nrdJ (gene name) kornec00230kornec00240kornec00480kornec00983kornec01100

Occurs in the following pathway maps:

Pathway Description
kornec00230 Purine metabolism
kornec00240 Pyrimidine metabolism
kornec00480 Glutathione metabolism
kornec00983 Drug metabolism - other enzymes
kornec01100 Metabolic pathways

Sequences

Nucleotide sequence (GC-content: 67.4 %):

ATGACTGAGACCAAGACGGCGTCGCGCAGCACGACACCGGCCTCCTCGGGCCTGCCCGTTCGCAGGGTGTTCAGCACCGAGGGGGTGCATCCCTATGACGAGGTCACCTGGCAGCGCCGTGACGTCGTCCAGAAGAACTGGCGCACCGGAGAGGTCGTCTTCGAGCAGCGCGGCGTCGAGTTCCCCGATTTCTGGAGCGTCAACGCCTCCACGATCGTCACCAACAAGTACTTCCGCGGTGCCCTGGGGACCCCGGCCCGCGAGGACAGCCTCAAGACCCTCATCGACCGGGTCGTGAAGACCTACGTGAGGGCCGGTCAGGACAACGGCTACTTCGCCAGCGCCAAGGACGCCAAGGTCTACAGCGAGGAGCTCACCTGGCTGCTGGTCCACCAGTACTTCAGCTTCAACTCCCCGGTCTGGTTCAACGTCGGGACCACCAGTCCCCAGCAGGTCAGTGCCTGCTTCATCCTGTCGGTCGACGACTCGATGGAGTCGATCCTGAACTGGTACACCGAGGAGGGATTCATCTTCAAGGGCGGTTCCGGGGCCGGCGTGAACATCTCCCGGATCCGATCCTCCAAGGAGCTGCTGTCCTCGGGCGGTACCGCCTCGGGGCCGGTCTCCTTCATGCGCGGGGCCGATGCCTCGGCCGGCACCATCAAGTCCGGCGGAGCGACCCGCCGGGCCGCCAAGATGGTCGTGCTGGACGTCGACCACCCCGACATCGAGGAGTTCGTCGAGACCAAGGCGCGCGAGGAGGACAAGATCCGTGCGCTGCGCGATGCCGGCTTCGACATGGAGATCGGCGGCCGCGACATGGCCTCGGTCCAGTACCAGAACGCCAACAACTCGGTGCGCGTCTCCGACACCTTCATGACCGCCGTCGAGAAGGGCACCACGTTCGGTCTCACCTCCCGGGTCGAGCCCGGCAAGGTGATCGACGAGGTCGACGCCCGGCAGCTGTTCGGCAAGATCGCCCACGCCGCCTGGGAGTGCGCCGACCCCGGACTGCAGTACGACGACACCATCAACGCCTGGCACACCGACCCGAACACCGGGCGGATCAACGCGTCGAACCCCTGCTCGGAGTACATGAGCCTGGACAACTCCTCGTGCAACCTGGCCAGCCTCAACCTGCTCAAGTTCGTCGGGGCCGATGAGGTCTTCGACGTCGCCCGGTTCACCCGCGCCGTCGAGATCGTCATCACCGCGATGGACATCTCGATCTGCTTCGCCGACTTCCCGACCGAGTCGATCGGCCAGACCACCCGCGACTTCCGCCAGCTCGGCATCGGCTACGCCAACCTCGGCGCCCTGCTGATGGCGATGGGACTGGGCTACGACTCCGAGGGCGGGCGCAACCTGGCCGCCGCCATCACCTCCCTGATGACCGGCGTCGCCTACCGGCGCAGCGCCGAGCTGGCCGCCGTGGTCGGCCCCTACAACGGCTACGCCGCCAACGCCGAGCCCCACCAGGCCGTGATGCGCAAGCACCGCGACGCCAACAACGACGTCCACCCGCTGCACACCAACGACACCGCCGTGCTCACCGCCGCCCGTGCCGAGTGGGACCGGGTCGTCGAGCTGGGCGCCGAGAACGGGTTCCGCAACGCCCAGGCCTCGGTGCTGGCCCCCACCGGCACCATCGGCTTCATGATGGACTGCGACACCACCGGCATCGAGCCCGACTTCTCCCTGGTCAAGTTCAAGAAGATGGTCGACGGCTCCTCGATGCAGATCGTCAACCAGACCGTCCCGCGCGCCCTGACCAATCTCGGCTACTCCACCAGCGACGCCGACCAGATCGTCGCCTGGATCGCCGAGCACGGATCGGTGATCGGCGCCCCCCATCTCGACAAGGCCCACTACGAGGTCTTCGACTGCGCGATGGGCGAGCGGGCGATCGCCCCGATGGGCCACGTGCGGATGATGGCCGCCGTCCAGCCCTTCCTGTCGGGAGCCATCTCCAAGACCGTCAACCTGCCCGAGAGTGCCACCGTCGAGGACATCGCCGATGTCTACATGCAGAGCTGGAAGCTCGGCCTGAAGGCCGTCGCGGTCTACCGCGACAACTGCAAGGTCGGCCAGCCGCTGTCGGTGGAGACCACCGGCGACAAGGCCGGGGACAAGAAGGAGCCCGAGCCGGAGGTCCGCATCGAGTACCGGCCGCGCCGCCAGCGGCTGCCGAAGTCCCGGCTGGGTCGCACCACCAGCTTCCAGGTCGCCGGGGCCGGCGGATACCTCACCACCGGCGCCTACAACGATGGTCGGCTGGGAGAGATCTTCCTCAAGCTCGGCAAGCAGGGATCCACCCTGGCCGGCGCGATGGATGCCTTCTCGATCGCCATCTCCATCGGTCTGCAGTACGGAGTGCCGCTGGAGAGCTTCGTCCAGAAGTTCGCCAACATGAAGTTCGAGCCGGCCGGCATGACCGACGACTCGGACATCCGGATCGCCCAGTCGATCATCGACTACATCTTCCGGCGACTCGCCCTGGACTACCTGTCCTTCGACGAGCGGGCGGAGCTGGGGATCTACACCTCGGCCGAGCGGGCGCACTACGTCGAGACCGGCTCCTACCTGTCGGAGGAGGACGAGGCCGAGCTCATCGACTCCGAGAGCCTCAAGGAGACCCCGGCCGACCGGGTGCGGGTGCACGAGGACGGCGCCGCCCAGCCAGGGCTGTTCGACCCGACGCCGGCCCCCGAGCACGTCGGCGGGGCCCACACCAGCGCCGAACTGCTGGAGGAGCAGCTCGGCCGTGAGGTCGACGCCCCGCTGTGCATGACCTGCGGCACCAAGATGCGGCCCTCCGGATCCTGCTACGTCTGCGAGGGATGCGGCTCGACCAGCGGCTGCAGCTGA

Protein sequence:

MTETKTASRSTTPASSGLPVRRVFSTEGVHPYDEVTWQRRDVVQKNWRTGEVVFEQRGVEFPDFWSVNASTIVTNKYFRGALGTPAREDSLKTLIDRVVKTYVRAGQDNGYFASAKDAKVYSEELTWLLVHQYFSFNSPVWFNVGTTSPQQVSACFILSVDDSMESILNWYTEEGFIFKGGSGAGVNISRIRSSKELLSSGGTASGPVSFMRGADASAGTIKSGGATRRAAKMVVLDVDHPDIEEFVETKAREEDKIRALRDAGFDMEIGGRDMASVQYQNANNSVRVSDTFMTAVEKGTTFGLTSRVEPGKVIDEVDARQLFGKIAHAAWECADPGLQYDDTINAWHTDPNTGRINASNPCSEYMSLDNSSCNLASLNLLKFVGADEVFDVARFTRAVEIVITAMDISICFADFPTESIGQTTRDFRQLGIGYANLGALLMAMGLGYDSEGGRNLAAAITSLMTGVAYRRSAELAAVVGPYNGYAANAEPHQAVMRKHRDANNDVHPLHTNDTAVLTAARAEWDRVVELGAENGFRNAQASVLAPTGTIGFMMDCDTTGIEPDFSLVKFKKMVDGSSMQIVNQTVPRALTNLGYSTSDADQIVAWIAEHGSVIGAPHLDKAHYEVFDCAMGERAIAPMGHVRMMAAVQPFLSGAISKTVNLPESATVEDIADVYMQSWKLGLKAVAVYRDNCKVGQPLSVETTGDKAGDKKEPEPEVRIEYRPRRQRLPKSRLGRTTSFQVAGAGGYLTTGAYNDGRLGEIFLKLGKQGSTLAGAMDAFSIAISIGLQYGVPLESFVQKFANMKFEPAGMTDDSDIRIAQSIIDYIFRRLALDYLSFDERAELGIYTSAERAHYVETGSYLSEEDEAELIDSESLKETPADRVRVHEDGAAQPGLFDPTPAPEHVGGAHTSAELLEEQLGREVDAPLCMTCGTKMRPSGSCYVCEGCGSTSGCS

GenBank Info

locus_tag - FAM19038-p1-1.1_002439
EC_number - 1.17.4.1
inference - COORDINATES: similar to AA sequence:RefSeq:WP_002523935.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - vitamin B12-dependent ribonucleotide reductase
protein_id - extdb:FAM19038-p1-1.1_002439

Gene Locus

Located on scaffold FAM19038-p1-1_scf1

Cellular location expand

Responsible annotations:
SL-0041: GO:0005618 cell wall
SL-0229: GO:0005622 intracellular anatomical structure
SL-0086: GO:0005737 cytoplasm
SL-0091: GO:0005829 cytosol
SL-0039: GO:0005886 plasma membrane
SL-0162: GO:0016020 membrane
FAM19038-p1-1.1_002438
FAM19038-p1-1.1_002440