update range to 10000 bp
locus tag: FAM19038-p1-1.1_002472 genome: FAM19038-p1-1.1
species: Acidipropionibacterium jensenii taxid: 1749

Annotations

Type Name Description Pathways
KEGG reaction
 R03270 2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Thiamin diphosphate kornec00010kornec00020kornec00620
KEGG reaction
 R01699 pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating); Pyruvate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2
KEGG reaction
 R00209 pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex; Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+ kornec01100kornec01110kornec01120kornec01200
KEGG reaction
 R00014 pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating); Pyruvate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + CO2 kornec00010kornec00020kornec00620
Gene Product
 pyruvate dehydrogenase (acetyl-transferring)- homodimeric type
Ortholog
 N0.HOG0002101 pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KEGG gene
 K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] kornec00010kornec00020kornec00620kornec01100kornec01110kornec01120kornec01200
Gene Ontology
 GO:1990204 oxidoreductase complex
Gene Ontology
 GO:1902494 catalytic complex
Gene Ontology
 GO:0071944 cell periphery
Gene Ontology
 GO:0055114 obsolete oxidation-reduction process
Gene Ontology
 GO:0046872 metal ion binding
Gene Ontology
 GO:0045254 pyruvate dehydrogenase complex
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0044444 obsolete cytoplasmic part
Gene Ontology
 GO:0044424 obsolete intracellular part
Gene Ontology
 GO:0043169 cation binding
Gene Ontology
 GO:0043167 ion binding
Gene Ontology
 GO:0032991 protein-containing complex
Gene Ontology
 GO:0030312 external encapsulating structure
Gene Ontology
 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors
Gene Ontology
 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Gene Ontology
 GO:0016491 oxidoreductase activity
Gene Ontology
 GO:0016020 membrane
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0005886 plasma membrane
Gene Ontology
 GO:0005737 cytoplasm
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005622 intracellular anatomical structure
Gene Ontology
 GO:0005618 cell wall
Gene Ontology
 GO:0005576 extracellular region
Gene Ontology
 GO:0005575 cellular_component
Gene Ontology
 GO:0005488 binding
Gene Ontology
 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity
Gene Ontology
 GO:0004738 pyruvate dehydrogenase activity
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Gene Ontology
 GO:0000287 magnesium ion binding
Eggnog Protein
 EP:aceE
Eggnog Ortholog
 EO:COG2609
Eggnog Description
 ED:Component of the pyruvate dehydrogenase (PDH) complex
EC Number
 EC:1.2.4.1 pyruvate dehydrogenase (acetyl-transferring); pyruvate decarboxylase (ambiguous); pyruvate dehydrogenase (ambiguous); pyruvate dehydrogenase (lipoamide); pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating); pyruvic acid dehydrogenase; pyruvic dehydrogenase (ambiguous) kornec00010kornec00020kornec00620kornec01100kornec01110kornec01120
Gene Code
 aceE

Occurs in the following pathway maps:

Pathway Description
kornec00010 Glycolysis / Gluconeogenesis
kornec00020 Citrate cycle (TCA cycle)
kornec00620 Pyruvate metabolism
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01120 Microbial metabolism in diverse environments
kornec01200 Carbon metabolism

Sequences

Nucleotide sequence (GC-content: 68.4 %):

GTGATCCCACGCGAAGAGCTCGGCCCTGTGCTGAACGGACTCCCGACCACCCTGCCCGACACCGATCCCGAGGAGACCCGGGAGTGGCTCGAGTCGCTCGACGCGATGGTCGGCGCGGAAGGTGAGAACCGGGCCCGGACCGTGCTGCTGAAGATGCTGGAGCACGCTCGGAGTCGCAGCAAGCTCGAGGTTCCCGCGCTCACCTCCACCGACTACATCAACACCATCTCCGCCGCCGACGAGGCGCCCTTCCCCGGCGACGAGAAGCTCGAGCAGCAGATTCGTCGGCTGCTCCGCTGGAACGCCGCGATCACCGTCCAGCGGGCCCAGCGTCCCGGTATCGGGGTCGGCGGTCACATCTCGACCTATGCCTCGGCGGTGACCCTCTACGAGGTGGGGATGAACCACTTCTGGCGCGGCCAGGACGCCCCCGGCGGTGGCGACCAGGTGTTCTTCCAGGGCCACGCGGCCCCGGGAATGTACGCCAGGGCGTTCCTCGAGGGACGGCTCAGCGAGGCCGATCTGGACGGCTTCCGCCAGGAGAAGTCCGCCGCCCCGCACGGCATGCCGTCCTACCCTCACCCGCGGATGATGCCGGAGTTCTGGCAGTTCCCGACGGTCTCGATGGGACTGGGCCCGATGGACGCCATCTACCAGGCGTCCTTCGACAAGTACCTCACCAACCGCGGTGTGAAGGACTGCTCCGACCAGCACGTCTGGGCCTTCCTCGGCGACGGCGAGATGGACGAGCCGGAGTCCCGCGGCTTCCTCCAGGTGGCCGCCAACGAGGAGCTGGACAACCTCACCTTTGTCATCAACTGCAACCTGCAGCGCCTGGACGGCCCGGTGCGCGGCAACGGCAAGATCGTCCAGGAGTTGGAGTCCACCTTCCGCGGCGCCGGCTGGAATGTCATCAAGGTGATCTGGGGATCGGGCTGGGACCCGCTGCTGGACGCCGACCACGACGGTGCCCTGGTCGATCTGATGAACAACACCCGCGACGGGGACTACCAGACCTTCAAGGCCAACGACGGCTCCTACGTGCGTCGGGAGTTCTTCGGCCGTGACCCGCGGACCCTGGCGATGGTGGAGCACTGGACCGACGACCAGATCTGGGCGCTGCGCCGCGGCGGGCACGACTACCGCAAGATGTACACCGCCTACAAGGCCGCGACCGAGACCAAGGGCGCACCGACCGTGGTGCTGGCCTGCACGATCAAGGGCTACGACCTGGGCTCCCACTTCGCCGGGCGCAACGCGACCCACCAGATGAAGAAGATGACTCTCGACGATCTCAAGTCCTTCCGGGACCGTCTGGACATCCCGATCTCCGACGCCGTGCTGGAGGCCGACCCCTACCGGGCGCCGTACTTCAACCCGGGACCCGAGGACGACCGGATCAAGTACCTGCTGGAGAGGCGACGGGCCCTCGGCGGCTTCGTGCCCGAGCGCAGGACCGCCCACAAGGCCCTGGCGCTGCCCGACGCCAGTCACTATGACGGCGTCAAGAGGGGGTCGGGCAAGCAGCAGGTGGCCACCACGATGGCCTTCGTCCGGCTGCTCAAGGACCTGATGCGGGACAAGGACTTCGCCCCGCGGGTGGTGCCGATCATTCCCGACGAGGCGCGCACCTTCGGGATGGACTCCTTCTTCCCGACGATCAAGATCTACAACCCGCACGGCCAGAACTACACCCCGGTCGACCACGAGCTGATGCTGAGCTACCGGGAGGCCCGCAACGGCCAGATCCTGCACACCGGCATCAACGAGGCGGGATCCACCGCCGCCTTCATCGCCGCCGGGACGGCGTACTCGACCCAGGGCATCGCGATGGTGCCGATCTACATCTTCTACTCGATGTTCGGTTTCCAGCGCACCGGCGACTCCTTCTGGGCGGCCGCCGACCAGATGGCCCGCGGGTTCATCCTCGGCGGCACCGCCGGGCGCACCACCCTGACCGGCGAGGGCACCCAGCACATGGACGGCCAGTCCCCGCTGCTGGCCTCGACCAATCCGGCGGTGGTCTCCTACGATCCCGCCTACGCCTACGAGATCGCCCACATCGTGGAGTCCGGCCTGCACCGGATGTACGGCCCCGATGACGAGGACGTGATGTTCTACCTCACCGTCTACAACGAGCCGATGGTCCAGCCCAAGGAGCCCGAGGACGTCGATGTCGAGGGCATCGTCAAGGGCATGCACCTGGTGCACCCGGGCTCCTTCGAGGGGGTCAACGCGGACGCCAGGCGCGCCCAGATCCTCGCCTCGGGGGTCGCGGTGCCGTGGGCCCTGGAGGCTCAGGACCTGCTCAAGGCCGATTTCGGGATCGTCGCCGACATCTGGAGCGTCACCTCCTGGACCGAGCTGCGCCGAGATGCGATGGACGCCGACGAGCAGGCCTTCCTGCACCCCGAGCAGGGCGCTCGCACCCCCTACCTGGTCCAGCGGCTGGACGGCGCCCCCGGCCCGGTGGTCGCGGTGAGCGACTACATGCGCCAGGTCCCCGACCAGATCGCCCAGTGGGTGCCCGGCGACTACGCCTCCCTGGGCGCCGACGGGTTCGGGTTCTCCGACACCCGCTCGGCGGCCCGCCGGTTCTTCCACATCGACGGCCCGTCGATCGCGGTGCGGGTGCTGCAGATGCTGGCGGCCAGGGGAGAGGTGCCCGCCGAGTGGCCGGCGCAGGCCGCCCGCAAGTACGACCTGCTCAATGTCAACGCCGGCACCTCGGGCAATGCCGGGGGCGACGCCTGA

Protein sequence:

MIPREELGPVLNGLPTTLPDTDPEETREWLESLDAMVGAEGENRARTVLLKMLEHARSRSKLEVPALTSTDYINTISAADEAPFPGDEKLEQQIRRLLRWNAAITVQRAQRPGIGVGGHISTYASAVTLYEVGMNHFWRGQDAPGGGDQVFFQGHAAPGMYARAFLEGRLSEADLDGFRQEKSAAPHGMPSYPHPRMMPEFWQFPTVSMGLGPMDAIYQASFDKYLTNRGVKDCSDQHVWAFLGDGEMDEPESRGFLQVAANEELDNLTFVINCNLQRLDGPVRGNGKIVQELESTFRGAGWNVIKVIWGSGWDPLLDADHDGALVDLMNNTRDGDYQTFKANDGSYVRREFFGRDPRTLAMVEHWTDDQIWALRRGGHDYRKMYTAYKAATETKGAPTVVLACTIKGYDLGSHFAGRNATHQMKKMTLDDLKSFRDRLDIPISDAVLEADPYRAPYFNPGPEDDRIKYLLERRRALGGFVPERRTAHKALALPDASHYDGVKRGSGKQQVATTMAFVRLLKDLMRDKDFAPRVVPIIPDEARTFGMDSFFPTIKIYNPHGQNYTPVDHELMLSYREARNGQILHTGINEAGSTAAFIAAGTAYSTQGIAMVPIYIFYSMFGFQRTGDSFWAAADQMARGFILGGTAGRTTLTGEGTQHMDGQSPLLASTNPAVVSYDPAYAYEIAHIVESGLHRMYGPDDEDVMFYLTVYNEPMVQPKEPEDVDVEGIVKGMHLVHPGSFEGVNADARRAQILASGVAVPWALEAQDLLKADFGIVADIWSVTSWTELRRDAMDADEQAFLHPEQGARTPYLVQRLDGAPGPVVAVSDYMRQVPDQIAQWVPGDYASLGADGFGFSDTRSAARRFFHIDGPSIAVRVLQMLAARGEVPAEWPAQAARKYDLLNVNAGTSGNAGGDA

GenBank Info

gene - aceE
locus_tag - FAM19038-p1-1.1_002472
EC_number - 1.2.4.1
inference - COORDINATES: similar to AA sequence:RefSeq:WP_002550752.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - pyruvate dehydrogenase (acetyl-transferring), homodimeric type
protein_id - extdb:FAM19038-p1-1.1_002472

Gene Locus

Located on scaffold FAM19038-p1-1_scf1

Cellular location expand

Responsible annotations:
SL-0243: GO:0005576 extracellular region
SL-0041: GO:0005618 cell wall
SL-0229: GO:0005622 intracellular anatomical structure
SL-0086: GO:0005737 cytoplasm
SL-0039: GO:0005886 plasma membrane
SL-0162: GO:0016020 membrane
FAM19038-p1-1.1_002471
FAM19038-p1-1.1_002473