update range to 10000 bp
locus tag: FAM19038-p1-1.1_002596 genome: FAM19038-p1-1.1
species: Acidipropionibacterium jensenii taxid: 1749

Annotations

Type Name Description Pathways
KEGG reaction
 R08165 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Isochorismate + 2-Oxoglutarate <=> 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate + CO2 kornec00130kornec01100kornec01110kornec01240
Ortholog
 N0.HOG0002067 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
Gene Code
 menD
KEGG gene
 K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9] kornec00130kornec01100kornec01110kornec01240
Gene Ontology
 GO:0071944 cell periphery
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0040007 growth
Gene Ontology
 GO:0016020 membrane
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0005886 plasma membrane
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005575 cellular_component
Eggnog Protein
 EP:menD
Eggnog Ortholog
 EO:COG1165
Eggnog Description
 ED:Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EC Number
 EC:2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase; SEPHCHC synthase; MenD kornec00130kornec01100kornec01110
Gene Product
 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase

Occurs in the following pathway maps:

Pathway Description
kornec00130 Ubiquinone and other terpenoid-quinone biosynthesis
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01240 Biosynthesis of cofactors

Sequences

Nucleotide sequence (GC-content: 72.9 %):

ATGCCTGAGACCCAGCCCTCCGAGGCCCAGCCTTCCAAGACAGGGCCATCCGAGACAGGGTCCGCCTCCGAGGTCGAGTCCGCACTGCGCTCCCGGTACCTGATCCGCGCCCTGGTCTCCCGAGGACTGCGAGAGGTCGTCTACTGTCCCGGATCCCGCGACGCACCCCTGGGATACGCCCTGGCCGCCGCCGAACAGGCCGGCTGGCTGCGCGTCCACGTCCGCCTCGACGAGCGCACGGCCGGATTCATGGCCCTGGGCCTGTCCCGCGCCGCCGTCCTGCAGGGCCGCAGCACCCCGGCGGCGGTCGTGACCACCTCGGGCACCGCGGTGGCGAACCTGCATCCCGCGGTGCTGGAGGCCGATGCCGCCGGCGTCCCGCTGCTGCTGCTCACCGCCGACCGGCCCCACGAGATGTGGCACACCCGGGCCAACCAGACCACCGTCCAGGAGGGGATCTTCGGCTCCGCGACCCGGTTCTCGGCCACACTTCCGGCCGGCTACCCGGCCGATTCGCGGCTGGACGGGCTGGTCGGTCGCACGATGGCAGCCGCCACCGGCGAGTTCAGCGCGGACCCCGGACCGGTGCACCTGGATGTCTGCTTCCGCGACCCCCTGGTGCCCGACCGGGCGTGGCTCCCCGGTCAGCCACCGGAGGTCTCGACCCCCGCACGACGGGTTGAGCCCGTCGGGCCGCTCGTCGAGATGCCGGCCCGCAGTGTCGTGGTCGCCGGAGACGCCGCGGGGGGACGGGCCCGGGAGCTCTCCGAGGAGCACGGATGGCCGTTGCTGGCCGAACCCAGCTCGGGTGCCCGGTCGGGTCGCACCGCCCTTGTCGACTACCAAGGGTTGCTCTCCACCTCACTGGCCGACGACATCGAGGGGGTCCTGGTTCTGGGCCATCCGACCCTGTCGCGGCCGGTCTCGCGACTACTGGCCCGCACCGACATCCCGATCACCGTCATCACCGACTCCCCGCGGTGGACCGATGTCGCCGGGGTGGGACGGCCGGTCGCCGCCCCCGGGAAGATCCGCGCGAGGGGGGAGGACGAGTCCTGGCTGGACCGCTGGCACAGTGCCGACCACCGCACGGACCACCCGGATGGCGGCTCTCCAGACGGCTCTGTCGACGGCGCCTCCGGGGCGGCCGCTGAGAAGAACCGCGCCGCCGCGATGATCTGGCAGGCCTCCTGCACTCCCGGAGGACCGGCTCTGATGATCGGCGCCTCGGCGGTGATCCGCTCCTTCGACCGGCACGCCGTGCCCGGAGCGGTGGCTCCGACAGCGGTGGCCAACCGTGGGCTGGCCGGTATTGACGGCACCGTCTCGACGGCGGTGGGCTTGTCGACGGGGTTGGGCCGTCCGGTCCGCGCGGTGGTGGGCGACCTCACCGCCGTCCACGACGCCACCGGTCTGCTGACCGGGCGGCGCGAGTGTCAGGCCGACGTCCAGGTGATCGTTCTCAACGACTCGGGCGGGGCGATCTTTGCCGGCCTGGAGCATGCCCGGGCCCCCCACGACGTCCTGGAGAGGTTCTTCCTCACCCCGCAGAGGATCGACCTCGCCCACCTGGCCGCGGCGCTGGGGGCCGACTTCCAGCGGGTCGACGTCGACGGCCTGCCCGCCGTTCTGGAGCGTCCGGTGACCGGGCGAGGCATCGTCGAGGTGACCCTGCTCACCGGACTCTCCTGA

Protein sequence:

MPETQPSEAQPSKTGPSETGSASEVESALRSRYLIRALVSRGLREVVYCPGSRDAPLGYALAAAEQAGWLRVHVRLDERTAGFMALGLSRAAVLQGRSTPAAVVTTSGTAVANLHPAVLEADAAGVPLLLLTADRPHEMWHTRANQTTVQEGIFGSATRFSATLPAGYPADSRLDGLVGRTMAAATGEFSADPGPVHLDVCFRDPLVPDRAWLPGQPPEVSTPARRVEPVGPLVEMPARSVVVAGDAAGGRARELSEEHGWPLLAEPSSGARSGRTALVDYQGLLSTSLADDIEGVLVLGHPTLSRPVSRLLARTDIPITVITDSPRWTDVAGVGRPVAAPGKIRARGEDESWLDRWHSADHRTDHPDGGSPDGSVDGASGAAAEKNRAAAMIWQASCTPGGPALMIGASAVIRSFDRHAVPGAVAPTAVANRGLAGIDGTVSTAVGLSTGLGRPVRAVVGDLTAVHDATGLLTGRRECQADVQVIVLNDSGGAIFAGLEHARAPHDVLERFFLTPQRIDLAHLAAALGADFQRVDVDGLPAVLERPVTGRGIVEVTLLTGLS

GenBank Info

gene - menD
locus_tag - FAM19038-p1-1.1_002596
EC_number - 2.2.1.9
inference - COORDINATES: similar to AA sequence:RefSeq:WP_002537039.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase
protein_id - extdb:FAM19038-p1-1.1_002596

Gene Locus

Located on scaffold FAM19038-p1-1_scf1

Cellular location expand

Responsible annotations:
SL-0039: GO:0005886 plasma membrane
SL-0162: GO:0016020 membrane
FAM19038-p1-1.1_002595
FAM19038-p1-1.1_002597