update range to 10000 bp
locus tag: FAM19471-i1-1.1_000276 genome: FAM19471-i1-1.1
species: Limosilactobacillus fermentum taxid: 1613

Annotations

Type Name Description Pathways
KEGG reaction
 R02024 2'-deoxycytidine diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dCDP + Thioredoxin disulfide + H2O <=> Thioredoxin + CDP kornec00240kornec01100
KEGG reaction
 R02019 2'-deoxyguanosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dGDP + Thioredoxin disulfide + H2O <=> GDP + Thioredoxin kornec00230kornec01100
KEGG reaction
 R02018 2'-deoxyuridine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dUDP + Thioredoxin disulfide + H2O <=> Thioredoxin + UDP kornec00240kornec01100
KEGG reaction
 R02017 2'-deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dADP + Thioredoxin disulfide + H2O <=> Thioredoxin + ADP kornec00230kornec01100
Gene Code
 nrdE
Ortholog
 N0.HOG0003483 class 1b ribonucleoside-diphosphate reductase subunit alpha
KEGG gene
 K00525 E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] kornec00230kornec00240kornec01100
Eggnog Protein
 EP:nrdE
Eggnog Ortholog
 EO:COG0209
Eggnog Description
 ED:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC Number
 EC:1.17.4.1 ribonucleoside-diphosphate reductase; ribonucleotide reductase (ambiguous); CDP reductase; ribonucleoside diphosphate reductase; UDP reductase; ADP reductase; nucleoside diphosphate reductase; ribonucleoside 5'-diphosphate reductase; ribonucleotide diphosphate reductase; 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; RR; nrdB (gene name); nrdF (gene name); nrdJ (gene name) kornec00230kornec00240kornec00480kornec00983kornec01100
Gene Product
 class 1b ribonucleoside-diphosphate reductase subunit alpha

Occurs in the following pathway maps:

Pathway Description
kornec00230 Purine metabolism
kornec00240 Pyrimidine metabolism
kornec00480 Glutathione metabolism
kornec00983 Drug metabolism - other enzymes
kornec01100 Metabolic pathways

Sequences

Nucleotide sequence (GC-content: 51.3 %):

ATGGCTCTTTCAGAAATTGATATGACCAAGGTGAAGTACTTCGACCTAAACAACGAGATCAACATCCCCAAGGATGGTCAAATCCAGTTGAACCTCGATCAAGAAGCCCTAGACGACTTTATTAAGGAAAACGTGGAACCAAACACCAAGAAGTTCTCCTCCGTAATGGAACGGCTAAACTGGTTAATCGAAAACGACTACCTCGAAGAAGACTTTATTCGCCAATATACGCCCGCCTTTTTAGATCGACTCTACCAATACTTAAAGGAACAAGACTTCCACTTCCACTCCTTTATGGCCGCCTACAAATTTTACGCCCAATACGCCATGCGGACCAACGACAAGGAATACTACCTGGAAAACTACATCGACCGGGTGGCTATGAACGCCTTGTACCTAGCCAACGGGGACGAACAACTGGCCATGGACCTGGCTGATGAGTTAATCCACCAACGCTACCAACCGGCCACGCCAACCTTCTTAAACGTTGGTCGCAAGCGGCGCGGGGAATTCGTTTCCTGCTTTGAAATCCAAGCTACCGATGACATGAACACGATCGGGCGGACGATCAACTCCGCTTTGCAACTATCCAAGATCGGTGGCGGGGTCGGCATCAACTTAAATAACCTCCGCGAAGCCGGCGCCCCAATCAAGAAGATCAAGGGAGCCGCTTCCGGGGTTGTCCCGGTCATGAAGCTCTTAGAAGACGCCTTTTCATACTCCAACCAACTGGGGCAGCGCCAAGGAGCGGGGGTTGTTTACCTCTCCGTCTTCCACCCCGACATCATTGACTTTTTGGGGGCCAAAAAGGAAAACGCCGACGAAAAGGTTCGCTTAAAGACCCTTTCCCTGGGGGTAACGGTGCCGGACAAGTTCTACCAGTTAGTGGAAGAAGACGCCCCAATGTACCTCTTCTCCCCGTACGACGTGGAACGAATCTACGGTAAGCCCTTCTCTTACGTTGACATCACCAAGGAATACGACAACCTGGTTGCTAACCCTGAAATCACCAAGAAGAAGGTCAACGCCCGTGAGTTGGAAGACGAAATCTCCAAGTTACAACAAGAATCTGGCTACCCATACATTGTTAACGTCGATACGGTTAACAAGGCCAACCCAATTGAAGGAACAATCGTAATGTCTAACCTCTGTTCCGAAATTGCCCAAGTTCAGATTCCGTCCCGGGTCAACGATGACCAAACCTACGAAACCCTCGGCACCGACGTTTCTTGTAACCTCGGTTCCACAAACATCGCTAACCTGATGGAAACACCAGACCTCGGACGCTCCGTTCGGGCGATGATGCGTGGTCTGACCCACATTTCCGATGCTGAAAGCTTAACCGTAGTCCCATCCATCAAGCACGGCAACGACCTTTTCCACTCGGTTGGGTTAGGAGCGATGGGGCTACACGGCTTCTTAGCTAAGCACCACATCATGTACGGTTCTCCGGTTGCCCTTGAGTTCACCAGCGTTTACTTCATGCTTTTAAACTACTGGACCTTAGTGGCTTCTAACGAAATCGCCCAGGAAAAGGGTGAAAACTTTGCCAACTTCGAACGGTCTGCCTACGCTGACGGTTCCTACTTTGACAAGTACCTGACTAAGGACTGGGGGCCAAAGTCCGCCGCCGTTAAGGAACTCTTTGCCGGCTTCTTTATCCCAACCCCAGACGACTGGCAAGAACTCAAGCAACGGGTTCAAGAATCCGGTCTCTACAATGCCTACCGCCTCGCCGTGGCACCGAACGGCTCGACCTCTTACATTGGGGACTCCACGTCTAGCCTACACCCCATCATCAACCGGATCGAAGAACGGCAAGAAAAGATGATTGGTAAGGTCTACTACCCGGCCCCATACCTATCCAACGACACGATGCCGTACTACCGCTCCGCTTACGATACGGACATGCGTAGCGTCATTGATACCTACGCCGCCGCCCAGGAACACGTCGACCAGTCCCTGTCGATGACCCTGTTCATGCGCTCGACCATTCCAGCCGGCATGTACGAATGGAAGGACGGGCGGACGGAAAAGATGACCACCCGCGACCTAAACATCCTTCGTCACTACGCCCACCAAAAGGGCATTAAGTCGATTTACTACATCCGGACCTTCACGGATGATAACGAAGAAGTCGGCGCCAACCAATGTGAATCTTGCGTAATTTAA

Protein sequence:

MALSEIDMTKVKYFDLNNEINIPKDGQIQLNLDQEALDDFIKENVEPNTKKFSSVMERLNWLIENDYLEEDFIRQYTPAFLDRLYQYLKEQDFHFHSFMAAYKFYAQYAMRTNDKEYYLENYIDRVAMNALYLANGDEQLAMDLADELIHQRYQPATPTFLNVGRKRRGEFVSCFEIQATDDMNTIGRTINSALQLSKIGGGVGINLNNLREAGAPIKKIKGAASGVVPVMKLLEDAFSYSNQLGQRQGAGVVYLSVFHPDIIDFLGAKKENADEKVRLKTLSLGVTVPDKFYQLVEEDAPMYLFSPYDVERIYGKPFSYVDITKEYDNLVANPEITKKKVNARELEDEISKLQQESGYPYIVNVDTVNKANPIEGTIVMSNLCSEIAQVQIPSRVNDDQTYETLGTDVSCNLGSTNIANLMETPDLGRSVRAMMRGLTHISDAESLTVVPSIKHGNDLFHSVGLGAMGLHGFLAKHHIMYGSPVALEFTSVYFMLLNYWTLVASNEIAQEKGENFANFERSAYADGSYFDKYLTKDWGPKSAAVKELFAGFFIPTPDDWQELKQRVQESGLYNAYRLAVAPNGSTSYIGDSTSSLHPIINRIEERQEKMIGKVYYPAPYLSNDTMPYYRSAYDTDMRSVIDTYAAAQEHVDQSLSMTLFMRSTIPAGMYEWKDGRTEKMTTRDLNILRHYAHQKGIKSIYYIRTFTDDNEEVGANQCESCVI

GenBank Info

gene - nrdE
locus_tag - FAM19471-i1-1.1_000276
EC_number - 1.17.4.1
inference - COORDINATES: similar to AA sequence:RefSeq:WP_019253642.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - class 1b ribonucleoside-diphosphate reductase subunit alpha
protein_id - extdb:FAM19471-i1-1.1_000276

Gene Locus

Located on scaffold FAM19471-i1-1_scf3

FAM19471-i1-1.1_000275
FAM19471-i1-1.1_000277