update range to 10000 bp
locus tag: FAM19471-i1-1.1_000785 genome: FAM19471-i1-1.1
species: Limosilactobacillus fermentum taxid: 1613

Annotations

Type Name Description Pathways
Gene Product
 thymidylate synthase
KEGG reaction
 R02101 5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase; dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP kornec00240kornec00670kornec01100
Ortholog
 N0.HOG0001216 thymidylate synthase
KEGG gene
 K00560 thyA, TYMS; thymidylate synthase [EC:2.1.1.45] kornec00240kornec00670kornec01100kornec01523
Gene Ontology
 GO:1901576 organic substance biosynthetic process
Gene Ontology
 GO:1901362 organic cyclic compound biosynthetic process
Gene Ontology
 GO:1901360 organic cyclic compound metabolic process
Gene Ontology
 GO:1901293 nucleoside phosphate biosynthetic process
Gene Ontology
 GO:1901137 carbohydrate derivative biosynthetic process
Gene Ontology
 GO:1901135 carbohydrate derivative metabolic process
Gene Ontology
 GO:0090407 organophosphate biosynthetic process
Gene Ontology
 GO:0071704 organic substance metabolic process
Gene Ontology
 GO:0055086 nucleobase-containing small molecule metabolic process
Gene Ontology
 GO:0046483 heterocycle metabolic process
Gene Ontology
 GO:0046385 deoxyribose phosphate biosynthetic process
Gene Ontology
 GO:0044281 small molecule metabolic process
Gene Ontology
 GO:0044271 cellular nitrogen compound biosynthetic process
Gene Ontology
 GO:0044249 cellular biosynthetic process
Gene Ontology
 GO:0044238 primary metabolic process
Gene Ontology
 GO:0044237 cellular metabolic process
Gene Ontology
 GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
Gene Ontology
 GO:0034654 nucleobase-containing compound biosynthetic process
Gene Ontology
 GO:0034641 cellular nitrogen compound metabolic process
Gene Ontology
 GO:0032259 methylation
Gene Ontology
 GO:0019692 deoxyribose phosphate metabolic process
Gene Ontology
 GO:0019637 organophosphate metabolic process
Gene Ontology
 GO:0019438 aromatic compound biosynthetic process
Gene Ontology
 GO:0018130 heterocycle biosynthetic process
Gene Ontology
 GO:0016741 transferase activity, transferring one-carbon groups
Gene Ontology
 GO:0016740 transferase activity
Gene Ontology
 GO:0009987 cellular process
Gene Ontology
 GO:0009394 2'-deoxyribonucleotide metabolic process
Gene Ontology
 GO:0009265 2'-deoxyribonucleotide biosynthetic process
Gene Ontology
 GO:0009263 deoxyribonucleotide biosynthetic process
Gene Ontology
 GO:0009262 deoxyribonucleotide metabolic process
Gene Ontology
 GO:0009165 nucleotide biosynthetic process
Gene Ontology
 GO:0009117 nucleotide metabolic process
Gene Ontology
 GO:0009058 biosynthetic process
Gene Ontology
 GO:0008168 methyltransferase activity
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0006807 nitrogen compound metabolic process
Gene Ontology
 GO:0006796 phosphate-containing compound metabolic process
Gene Ontology
 GO:0006793 phosphorus metabolic process
Gene Ontology
 GO:0006753 nucleoside phosphate metabolic process
Gene Ontology
 GO:0006725 cellular aromatic compound metabolic process
Gene Ontology
 GO:0006139 nucleobase-containing compound metabolic process
Gene Ontology
 GO:0004799 thymidylate synthase activity
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Eggnog Protein
 EP:thyA
Eggnog Ortholog
 EO:COG0207
Eggnog Description
 ED:Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5
EC Number
 EC:2.1.1.45 thymidylate synthase; dTMP synthase; thymidylate synthetase; methylenetetrahydrofolate:dUMP C-methyltransferase; TMP synthetase kornec00240kornec00670kornec01100

Occurs in the following pathway maps:

Pathway Description
kornec00240 Pyrimidine metabolism
kornec00670 One carbon pool by folate
kornec01100 Metabolic pathways
kornec01523 Antifolate resistance

Sequences

Nucleotide sequence (GC-content: 54.5 %):

ATGACGGTAAATCATAATGAAGAACAGTACCTAGACCTGGCGCGCCACGTCCTGGAATTCGGTGACCAAAAGGGGGACCGGACCGGAACCGGAACTAAGTCGGTCTTCGGCTACCAGATGCGCTTTAACCTGCAGGAAGGTTTCCCGATCCTGACGACCAAGAAGGTGGCCTTTGGGCTGGTCAAAAGCGAGCTCCTCTGGTTCTTGCGCGGCGACACCAACATCCGCTTTCTCTTGGAACACAAAAACCACATCTGGGACGAGTGGGCCTTTAAGAAGTGGGTCGAAAGCGACGAGTATACGGGCCCGGACATGACCGACTTTGGCCGCCGTTCCTTGGTGGATGCCGCATTTAACGAAGAGTACAAAAAGGAAAAGCGGGCCTTTTGCCAGCGGATCTTAGAGGATGACGACTTTGCTAAGCAGTACGGCAACCTAGGTTTGGTGTACGGCTCCCAGTGGCGGAGTTGGCAAACGCCAAACGGCCCGGTTGACCAAATCAAAAAGGTGATCGAGCAGATTAAGACCAATCCCGATTCTCGGCGGTTGATCGTAACGGCTTGGAACCCGGCCGACGTCGATAACATGGCCCTGCCACCGTGCCACACAATGTTCCAGTTTTACGTGAACAACGGCAAGCTGTCTTGCCAGCTTTACCAGCGCAGTGCCGACATCTTCTTAGGGGTACCGTTTAACATCGCCTCTTACGCCTTACTGACCCACATGATTGCGCACCAGTGCGGGCTGGAAGTTGGGGAATTTGTCCACACCTTGGGGGACGCTCACATCTACTTAAACCACCTCGATCAGATTAAAGAACAGCTCAGCCGCCCAGTTCACCAGGCACCGCAGCTGATCTTGCCGGCGGAGGCCAAGCCAATTGACGAGTACCAAATGGAAGACATCAAGCTGGAGGGCTACGAACACGAAGACGCCATTAAGGCCCCGGTAGCGGTCTAA

Protein sequence:

MTVNHNEEQYLDLARHVLEFGDQKGDRTGTGTKSVFGYQMRFNLQEGFPILTTKKVAFGLVKSELLWFLRGDTNIRFLLEHKNHIWDEWAFKKWVESDEYTGPDMTDFGRRSLVDAAFNEEYKKEKRAFCQRILEDDDFAKQYGNLGLVYGSQWRSWQTPNGPVDQIKKVIEQIKTNPDSRRLIVTAWNPADVDNMALPPCHTMFQFYVNNGKLSCQLYQRSADIFLGVPFNIASYALLTHMIAHQCGLEVGEFVHTLGDAHIYLNHLDQIKEQLSRPVHQAPQLILPAEAKPIDEYQMEDIKLEGYEHEDAIKAPVAV

GenBank Info

locus_tag - FAM19471-i1-1.1_000785
EC_number - 2.1.1.45
inference - COORDINATES: similar to AA sequence:RefSeq:WP_003666060.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - thymidylate synthase
protein_id - extdb:FAM19471-i1-1.1_000785

Gene Locus

Located on scaffold FAM19471-i1-1_scf11

FAM19471-i1-1.1_000784
FAM19471-i1-1.1_000786