update range to 10000 bp
locus tag: FAM19471-i1-1.1_001450 genome: FAM19471-i1-1.1
species: Limosilactobacillus fermentum taxid: 1613

Annotations

Type Name Description Pathways
Gene Code
 rfbB
KEGG reaction
 R06513 dTDPglucose 4,6-hydro-lyase; dTDP-glucose <=> dTDP-4-oxo-6-deoxy-D-glucose + H2O kornec00521kornec00523kornec00525kornec00541kornec01055kornec01100kornec01110
Ortholog
 N0.HOG0001056 dTDP-glucose 4,6-dehydratase
KEGG gene
 K01710 rfbB, rmlB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] kornec00521kornec00523kornec00525kornec00541kornec01055kornec01100kornec01110
Gene Ontology
 GO:1901576 organic substance biosynthetic process
Gene Ontology
 GO:0071704 organic substance metabolic process
Gene Ontology
 GO:0046379 extracellular polysaccharide metabolic process
Gene Ontology
 GO:0045226 extracellular polysaccharide biosynthetic process
Gene Ontology
 GO:0044264 cellular polysaccharide metabolic process
Gene Ontology
 GO:0044262 cellular carbohydrate metabolic process
Gene Ontology
 GO:0044260 cellular macromolecule metabolic process
Gene Ontology
 GO:0044249 cellular biosynthetic process
Gene Ontology
 GO:0044238 primary metabolic process
Gene Ontology
 GO:0044237 cellular metabolic process
Gene Ontology
 GO:0043170 macromolecule metabolic process
Gene Ontology
 GO:0034645 cellular macromolecule biosynthetic process
Gene Ontology
 GO:0034637 cellular carbohydrate biosynthetic process
Gene Ontology
 GO:0033692 cellular polysaccharide biosynthetic process
Gene Ontology
 GO:0016836 hydro-lyase activity
Gene Ontology
 GO:0016835 carbon-oxygen lyase activity
Gene Ontology
 GO:0016829 lyase activity
Gene Ontology
 GO:0016051 carbohydrate biosynthetic process
Gene Ontology
 GO:0009987 cellular process
Gene Ontology
 GO:0009059 macromolecule biosynthetic process
Gene Ontology
 GO:0009058 biosynthetic process
Gene Ontology
 GO:0008460 dTDP-glucose 4,6-dehydratase activity
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0005976 polysaccharide metabolic process
Gene Ontology
 GO:0005975 carbohydrate metabolic process
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Gene Ontology
 GO:0000271 polysaccharide biosynthetic process
Eggnog Protein
 EP:rfbB
Eggnog Ortholog
 EO:COG1088
Eggnog Description
 ED:Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EC Number
 EC:4.2.1.46 dTDP-glucose 4,6-dehydratase; thymidine diphosphoglucose oxidoreductase; TDP-glucose oxidoreductase; dTDP-glucose 4,6-hydro-lyase; dTDP-glucose 4,6-hydro-lyase (dTDP-4-dehydro-6-deoxy-alpha-D-glucose-forming) kornec00521kornec00523kornec00525kornec00541kornec01055kornec01100kornec01110
Gene Product
 dTDP-glucose 4-6-dehydratase

Occurs in the following pathway maps:

Pathway Description
kornec00521 Streptomycin biosynthesis
kornec00523 Polyketide sugar unit biosynthesis
kornec00525 Acarbose and validamycin biosynthesis
kornec00541 O-Antigen nucleotide sugar biosynthesis
kornec01055 Biosynthesis of vancomycin group antibiotics
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites

Sequences

Nucleotide sequence (GC-content: 43.8 %):

ATGGAAACTTTTAAGAATATTATTGTTACCGGGGGAGCCGGCTTTATCGGTTCCAACTTTGTTCACTATGTTGTTAACCACCACCCGGAAGTTGAACACATTACGGTTTTAGATAAACTGACTTATGCTGGTAATCCGGCTAATCTTGATGGCTTGCCAAAGAATAAAGTTGAACTCGTAGTCGGGGATATTTGTGATAAAGACTTAGTTGATAAGTTGGTAAGCAAAGCTGATGCAGTTGTGCATTATGCCGCGGAAAGTCACAATGACAACTCTTTGATTGATCCCACCCCGTTCATCCAAACTAATATTGTCGGAACTTCAGTTTTGATCAATGCTTGTCGGAAATATGACGTCCGTTATCACCATATTTCAACGGATGAAGTCTATGGGGATTTACCATTACGCGAAGATTTACCCGGTCATGGTGAAGGAAAAGGCGAAAAGTTTACTCCTGAATCACCATATAAGCCATCGAGTCCTTACTCTTCATCCAAGGCCAGTTCTGACTTATTAGTGCGGGCCTGGGTGCGGTCATTTGGTTTACGGGCTACAATCTCTAACTGTTCTAATAACTATGGTCCTTACCAACACATCGAAAAGTTTATTCCGCGTCAAATTACTAATATCTTAAGCGGTATTCGGCCGAAGCTTTATGGTTCAGGTAAAAACGTCCGTGACTGGATTCACACGAATGATCATTCTCGTGCGGTTTGGGATATTTTGACCAAGGGGAAGATTGGTGAAACCTACCTGATTGGTGCCGATGGTGAAAAGAACAATAAGGAAGTTCTCGAATTGATTCTGGAACTAACGGGTCAACCCAAGGATGCCTACGATCAGGTAAAAGATCGCCCTGGTCATGACTTGCGGTATGCGATTGACGCGACTAAGCTACGAACTGAACTCGGTTGGGAACCAGAGTACACTGACTTCAAGACGGGCTTGCAACACACCATTGACTGGTATACGGAACACCAAGATTGGTGGAAAGACGAAAAGGCGGCGGTCGAAGCCAAGTACGCTAAGAATGGTCAATAA

Protein sequence:

METFKNIIVTGGAGFIGSNFVHYVVNHHPEVEHITVLDKLTYAGNPANLDGLPKNKVELVVGDICDKDLVDKLVSKADAVVHYAAESHNDNSLIDPTPFIQTNIVGTSVLINACRKYDVRYHHISTDEVYGDLPLREDLPGHGEGKGEKFTPESPYKPSSPYSSSKASSDLLVRAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQITNILSGIRPKLYGSGKNVRDWIHTNDHSRAVWDILTKGKIGETYLIGADGEKNNKEVLELILELTGQPKDAYDQVKDRPGHDLRYAIDATKLRTELGWEPEYTDFKTGLQHTIDWYTEHQDWWKDEKAAVEAKYAKNGQ

GenBank Info

gene - rfbB
locus_tag - FAM19471-i1-1.1_001450
EC_number - 4.2.1.46
inference - COORDINATES: similar to AA sequence:RefSeq:WP_003664371.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - dTDP-glucose 4,6-dehydratase
protein_id - extdb:FAM19471-i1-1.1_001450

Gene Locus

Located on scaffold FAM19471-i1-1_scf31

FAM19471-i1-1.1_001449
FAM19471-i1-1.1_001451