update range to 10000 bp
locus tag: FAM19471-i1-1.1_000712 genome: FAM19471-i1-1.1
species: Limosilactobacillus fermentum taxid: 1613

Annotations

Type Name Description Pathways
Gene Product
 serine hydroxymethyltransferase
KEGG reaction
 R09099 5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase; L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O kornec00680kornec01100kornec01120
KEGG reaction
 R00945 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase; 5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine kornec00260kornec00460kornec00630kornec00670kornec00680kornec01100kornec01110kornec01120kornec01200kornec01230kornec01240
Ortholog
 N0.HOG0001462 glycine hydroxymethyltransferase
KEGG gene
 K00600 glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1] kornec00260kornec00460kornec00630kornec00670kornec00680kornec01100kornec01110kornec01120kornec01200kornec01230kornec01240kornec01523
Eggnog Protein
 EP:glyA
Eggnog Ortholog
 EO:COG0112
Eggnog Description
 ED:Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines
EC Number
 EC:2.1.2.1 glycine hydroxymethyltransferase; serine aldolase; threonine aldolase; serine hydroxymethylase; serine hydroxymethyltransferase; allothreonine aldolase; L-serine hydroxymethyltransferase; L-threonine aldolase; serine hydroxymethyltransferase; serine transhydroxymethylase kornec00260kornec00460kornec00630kornec00670kornec00680kornec01100kornec01110kornec01120

Occurs in the following pathway maps:

Pathway Description
kornec00260 Glycine, serine and threonine metabolism
kornec00460 Cyanoamino acid metabolism
kornec00630 Glyoxylate and dicarboxylate metabolism
kornec00670 One carbon pool by folate
kornec00680 Methane metabolism
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01120 Microbial metabolism in diverse environments
kornec01200 Carbon metabolism
kornec01230 Biosynthesis of amino acids
kornec01240 Biosynthesis of cofactors
kornec01523 Antifolate resistance

Sequences

Nucleotide sequence (GC-content: 55.3 %):

ATGGAATATGCAGGTAAGGACGCCCAACTTTGGGCCGCAATCGGACGCGAAGAACAACGCCAAGAGGACACGATTGAACTGATCGCCTCAGAAAACATTGTTTCAAAAGAAGTTGCCGCCGCACAGGGGTCTGTCTTAACCAACAAGTACGCTGAGGGGTACCCTGGCAAGCGCTACTACGGCGGTTGCCAATTTATTGACCAGGTGGAGCAACTCGCCATTGATCACGCTAAGGAACTCTTTGGCGCTGCCTACGCTAACGTTCAACCCCACTCCGGTTCCCAAGCTAACATGGCGGTCTACCAAGCATTATTAAAGCCTGGCGACACCATCTTGGGGATGGGGATGGACGCCGGGGGCCACTTAACCCACGGTTCCAAGGTTAATTTCTCCGGGAAGCTTTACCACACCTACGGTTACGAACTCAGTCCCGAAACCGAGGAACTGGATTACGACGCCATCCTGGCTCAGGCTAAGGAAATCCAACCCCAGTTGATCGTGGCGGGAGCGTCTGCTTACAGCCAAATCATCGACTGGGACAAGTTCCGCCAAATCGCCGATGAAGTGGGTGCTTACTTGATGGTCGACATGGCCCACATTGCCGGCCTGGTGGCTACGGGTTACCACCCGAACCCGGTTCCGGTTGCCGACGTTGTGACGACGACCACCCACAAGACTTTGCGTGGACCACGGGGCGGGATGATCCTATCCAAGTCTGAAGAACTAGGTAAGAAGTTTAACTCGGCCGTCTTCCCGGGTACGCAAGGGGGACCGCTGGAACACGTGATTGCCGGGAAGGCCCAGGCCTTTTACGAAGACTTACAACCAGCCTTTAAGGATTACATTGGCCAAGTGGTGAAAAACGCCGCGGCTATGGCGGAAGTGTTCAACGAATCCGAAACGATCCGGGTGGTCACTGGTGGGACGGCCAACCACTTGTTGGTCCTTGACCTAACGAAGACCGGCTTAACCGGTAAGGACGCCCAGGCCCTGCTCGATTCCGTGATGATCACCACTAACAAGGAAGCAATTCCAAATGACCAACGCAGCCCGTTTGTCACTTCCGGTCTGCGGGTCGGGACGCCAGCTATCACCTCGCGTGGCTTTAAAGAAGACGACGCCAAGCAGGTGGCCAGCCTGATTATCAAGGCGTTAGACAACGCTGACGACCAAACCATTTTGGCTGGAGTGAAAGAAGCCGTTCACGCCCTCACCCAGGCGCACCCGGTTGACTAA

Protein sequence:

MEYAGKDAQLWAAIGREEQRQEDTIELIASENIVSKEVAAAQGSVLTNKYAEGYPGKRYYGGCQFIDQVEQLAIDHAKELFGAAYANVQPHSGSQANMAVYQALLKPGDTILGMGMDAGGHLTHGSKVNFSGKLYHTYGYELSPETEELDYDAILAQAKEIQPQLIVAGASAYSQIIDWDKFRQIADEVGAYLMVDMAHIAGLVATGYHPNPVPVADVVTTTTHKTLRGPRGGMILSKSEELGKKFNSAVFPGTQGGPLEHVIAGKAQAFYEDLQPAFKDYIGQVVKNAAAMAEVFNESETIRVVTGGTANHLLVLDLTKTGLTGKDAQALLDSVMITTNKEAIPNDQRSPFVTSGLRVGTPAITSRGFKEDDAKQVASLIIKALDNADDQTILAGVKEAVHALTQAHPVD

GenBank Info

locus_tag - FAM19471-i1-1.1_000712
inference - COORDINATES: similar to AA sequence:RefSeq:WP_003685860.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - serine hydroxymethyltransferase
protein_id - extdb:FAM19471-i1-1.1_000712

Gene Locus

Located on scaffold FAM19471-i1-1_scf9

FAM19471-i1-1.1_000711
FAM19471-i1-1.1_000713