update range to 10000 bp
locus tag: FAM19471-i1-1.1_001334 genome: FAM19471-i1-1.1
species: Limosilactobacillus fermentum taxid: 1613

Annotations

Type Name Description Pathways
KEGG reaction
 R04560 10-Formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide kornec00230kornec00670kornec01100kornec01110
KEGG reaction
 R01127 IMP 1,2-hydrolase (decyclizing); IMP + H2O <=> 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide kornec00230kornec01100kornec01110
Gene Code
 purH
Ortholog
 N0.HOG0001442 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KEGG gene
 K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] kornec00230kornec00670kornec01100kornec01110kornec01523
Eggnog Protein
 EP:purH
Eggnog Ortholog
 EO:COG0138
Eggnog Description
 ED:Bifunctional purine biosynthesis protein PurH
EC Number
 EC:3.5.4.10 IMP cyclohydrolase; inosinicase; inosinate cyclohydrolase; IMP 1,2-hydrolase (decyclizing) kornec00230kornec01100kornec01110
EC Number
 EC:2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase; 5-amino-4-imidazolecarboxamide ribonucleotide transformylase; AICAR transformylase; 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase; 5-amino-4-imidazolecarboxamide ribotide transformylase; AICAR formyltransferase; aminoimidazolecarboxamide ribonucleotide transformylase kornec00230kornec00670kornec01100kornec01110
Gene Product
 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

Occurs in the following pathway maps:

Pathway Description
kornec00230 Purine metabolism
kornec00670 One carbon pool by folate
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01523 Antifolate resistance

Sequences

Nucleotide sequence (GC-content: 56.3 %):

ATGAAGCGCGCATTAGTTTCTGTATCGGACAAAACCAACTTGGTGCCCTTTGTAAAGGGGCTGGAAGAGTACGGCTACGAAATCGTCTCCACCGGGGGGACTAAGAAGGTCCTGGATGAGGCCGGCATTAAGACGATCTCGATTGAAGACGTCACCCACTTCCCGGAAATCTTGGACGGGCGGGTGAAAACCCTCAACCCTTACGTTCACGGGGGCCTGTTAGCCCGGCGCGACTTGCCGGAGCACATGAAGACCTTAGAAGACCTGTCGATCACCCCGATTGACCTGGTGTGCGTCAACCTCTACCCCTTCAAGGAAACGATCTTAAAGTCGGGCGTTGAACTGGCCGATGCGATCGAAAACATTGATATTGGTGGCCCGTCGATGGTCCGTTCGGCCGCTAAGAACTACCAAAGCGTCACGATCGTTACCGACATCAACGATTATGACCAGGTCCTGACCGAAATCGAAGAAAACGGCGATACGACCGCCGAAACCAAGGCCAAGTTAGGGGCCAAGGCCTTCCGGACCACCGCCGCTTATGACGCTTTGATCTCCCAGTACCTGACCGCTCAAGTGGGCCTGGAAGACCCGGAAAAGCTGACCCTGACTTACGACCTAAAGGAAACGATGCGCTACGGGGAAAACTCCCACCAACGCGCTTGGCTCTACGAAGACGCCCTGCCGAAGAGCTTCTCGATTTTGGAGGCCGAACAACTCCACGGCAAGAAGCTGTCCTGCAACAACATCAAGGACGCCGACGAAGCCCTGCGGTGCGTGCGTGAATTCGACGAACCAACCGTGGTGGCCATGAAGCACATGAACCCGTGTGGGATTGGCCGCGGCGACAGCCTGGAAGTCGCTTGGGACCGGGCCTACGAGGCTGATTCCGTTTCGATCTTCGGTGGCGTGATCGCCCTGAACCGCAAGGTCGACCTGGCGACCGCTGAAAAGATGCGGAAGATCTTCTTGGAAATCATCGTGGCGCCGGGCTTTGATGACGATGCCTTTGCGGTCTTGGCCAAGAAGAAGAACATCCGCCTCTTGCAAGTCGACTTTGACCAAAAGGACGAACCAACCAAGGAAGAAGTGGTTTCCGTGATGGGGGGACTCTTGATGCAAGACCAAGACACGCTTAAAGAGGACTGCCACGACTGGGAAGTGGTGACCGACGTTAAGCCAACCGAAGACCAATTGAAGGCAATGATGTTTGCTTGGAAGGCCGTTAAGCACGCTAAGTCCAACGCAATCGTGGTGGCCAACAATGAACGGACGCTAGGCGTGGGGGAAGGTCAACCAAACCGGATTGACTCCCTGAAGATCGCCGTCAAGCACGCCGGCGACTTGGTCGAAGGCAGCGTCTTGGCCTCCGATGCCTTCTTCCCGTTTGACGACTGCGTTAAGTACGCCGGCGAACACGGCGTCAAGGCGATCGTTCAACCAGGGGGCTCGGTACGCGACCAAGACTCGATTGACATGGCCAACAAGCTCGGGATCGCCATGGTGACGACCGGGGTGCGCCACTTTAGGCACTAA

Protein sequence:

MKRALVSVSDKTNLVPFVKGLEEYGYEIVSTGGTKKVLDEAGIKTISIEDVTHFPEILDGRVKTLNPYVHGGLLARRDLPEHMKTLEDLSITPIDLVCVNLYPFKETILKSGVELADAIENIDIGGPSMVRSAAKNYQSVTIVTDINDYDQVLTEIEENGDTTAETKAKLGAKAFRTTAAYDALISQYLTAQVGLEDPEKLTLTYDLKETMRYGENSHQRAWLYEDALPKSFSILEAEQLHGKKLSCNNIKDADEALRCVREFDEPTVVAMKHMNPCGIGRGDSLEVAWDRAYEADSVSIFGGVIALNRKVDLATAEKMRKIFLEIIVAPGFDDDAFAVLAKKKNIRLLQVDFDQKDEPTKEEVVSVMGGLLMQDQDTLKEDCHDWEVVTDVKPTEDQLKAMMFAWKAVKHAKSNAIVVANNERTLGVGEGQPNRIDSLKIAVKHAGDLVEGSVLASDAFFPFDDCVKYAGEHGVKAIVQPGGSVRDQDSIDMANKLGIAMVTTGVRHFRH

GenBank Info

gene - purH
locus_tag - FAM19471-i1-1.1_001334
EC_number - 2.1.2.3 --AND-- 3.5.4.10
inference - COORDINATES: similar to AA sequence:RefSeq:WP_003675886.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
protein_id - extdb:FAM19471-i1-1.1_001334

Gene Locus

Located on scaffold FAM19471-i1-1_scf27

FAM19471-i1-1.1_001333
FAM19471-i1-1.1_001335